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S5451

Sarpogrelate hydrochloride

≥98% (HPLC)

Synonym(s):

Anplag, Butanedioic acid 1-[2-(dimethylamino)-1-[[2-[2-(3-methoxyphenyl)ethyl]phenoxy]methyl]ethyl] ester hydrochloride, MCI 9042, Succinic acid mono-(1-dimethylaminomethyl-2-(2-[2-(3-methoxyphenyl)et hyl]phenoxy)ethyl) ester hydrochloride

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5 mg

Available to ship TODAYfromMILWAUKEE

$93.30
$79.30
25 mg

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$252.00

About This Item

Empirical Formula (Hill Notation):
C24H31NO6.HCl
CAS Number:
135159-51-2
Molecular Weight:
465.97
NACRES:
NA.77
PubChem Substance ID:
329824454
UNSPSC Code:
12352200
MDL number:
MFCD00887582
Assay:
≥98% (HPLC)
Form:
solid
Storage condition:
desiccated

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Quality Segment

100

assay

≥98% (HPLC)

form

solid

storage condition

desiccated

solubility

deionized water: ≥5 mg/mL

storage temp.

room temp

SMILES string

Cl.COc1cccc(CCc2ccccc2OCC(CN(C)C)OC(=O)CCC(O)=O)c1

InChI

1S/C24H31NO6.ClH/c1-25(2)16-21(31-24(28)14-13-23(26)27)17-30-22-10-5-4-8-19(22)12-11-18-7-6-9-20(15-18)29-3;/h4-10,15,21H,11-14,16-17H2,1-3H3,(H,26,27);1H

InChI key

POQBIDFFYCYHOB-UHFFFAOYSA-N

General description

Sarpogrelate hydrochloride binds to the serotonin receptor (5-hydroxytryptamine, 5-HT2A). Its binding to 5-HT2A receptor inhibits thrombus formation and reduces platelet aggregation. Sarpogrelate hydrochloride has been used as an anti-atherosclerotic agent. It improves the endothelial function and may be useful for treating peripheral arterial disease. Use of sarpogrelate hydrochloride as 5-HT2A antagonist reduces urinary albumin levels in diabetic nephropathy.

Biochem/physiol Actions

Sarapogrelate hydrochloride is a potent and selective 5-HT2A receptor antagonist.
Sarapogrelate hydrochloride is a potent and selective 5-HT2A receptor antagonist. It exhibits analgesic effects in numerous animal studies.

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Sarpogrelate hydrochloride ≥98% (HPLC)

Sigma-Aldrich

S5451

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Sigma-Aldrich

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Sigma-Aldrich

SML2209

Benactyzine hydrochloride

form

solid

form

powder

form

powder

form

powder

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

-

storage temp.

room temp

storage temp.

room temp

storage temp.

2-8°C

storage temp.

2-8°C

storage condition

desiccated

storage condition

desiccated

storage condition

desiccated

storage condition

desiccated

solubility

deionized water: ≥5 mg/mL

solubility

H2O: 5 mg/mL (clear solution, warmed)

solubility

DMSO: >20 mg/mL, H2O: >20 mg/mL

solubility

H2O: 2 mg/mL, clear

pictograms

Exclamation markEnvironment
GHS07,GHS09

signalword

Warning

hcodes

H302,H410

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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