PENK

Penicillin G Kaliumsalz

95.0 - 102.0%

• Synonym(e): Benzylpenicillin Kaliumsalz
• Empirische Formel (Hill-System): C₁₆H₁₇KN₂O₄S
• CAS-Nummer: 113-98-4
• Molekulargewicht: 372.48
• UNSPSC Code: 51283424
• NACRES: NA.85
• PubChem Substance ID: 57654576
• EC Number: 204-038-0
• Beilstein/REAXYS Number: 3832841
• MDL number: MFCD00036193

Eigenschaften

• Quality Segment: 200
• assay: 95.0 - 102.0%
• form: powder
• antibiotic activity spectrum: Gram-negative bacteria, Gram-positive bacteria
• mode of action: cell wall synthesis | interferes
• SMILES string: [K+].[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)Cc3ccccc3)C([O-])=O
• InChI: 1S/C16H18N2O4S.K/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9;/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22);/q;+1/p-1/t11-,12+,14-;/m1./s1
• InChI key: IYNDLOXRXUOGIU-LQDWTQKMSA-M

Beschreibung

Application

Penicillin G is a narrow spectrum antibiotic derived from Streptococcus pneumoniae. It is the drug of choice for groups A, B, C and G streptococci, nonenterococcal group D streptococci, viridians group streptococci, and non-penicillinase producing staphylococcus. The potassium salt has been used to study murosomes of staphylococci† and the penicillin-induced lysis of Streptococcus mutans†.

Biochem/physiol Actions

Wirkungsweise: Penicillin G wirkt durch Hemmung der Zellwandsynthese durch die Bindung an Penicillin bindende Proteine (PBP), um die Vernetzung der Peptidoglycan-Kette zu hemmen.

Antimikrobielles Spektrum: Diese Produkt ist wirksam gegen grampositive und gramnegative Bakterien.

Packaging

1mu,10mu,100mu

Other Notes

Keep container tightly closed in a dry and well-ventilated place. Handle and store under inert gas. Keep in a dry place.Very soluble in water, slightly soluble in ethanol (96%), practically insoluble in methylene chloride

Disclaimer

Solutions should be filter sterilized and stored at 2-8°C for 1 week or at -20°C for more lengthy periods. Solutions are stable at 37°C for 3 days.

Sicherheitshinweise

• pictograms: GHS07
• signalword: Warning
• hcodes: H317
• pcodes: P280
• Hazard Classifications: Skin Sens. 1
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves