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Merck

M6882

Methyl α-D-Mannopyranosid

≥99.0% (HPLC)

Synonym(e):

Methyl-α-D-mannosid

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25 G

€ 63,80

100 G

€ 192,00

500 G

€ 820,00

€ 63,80


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Über diesen Artikel

Empirische Formel (Hill-System):
C7H14O6
CAS-Nummer:
Molekulargewicht:
194.18
UNSPSC Code:
12352201
NACRES:
NA.25
PubChem Substance ID:
EC Number:
210-502-3
Beilstein/REAXYS Number:
81566
MDL number:

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Quality Level

assay

≥99.0% (HPLC)

form

powder or crystals

optical activity

[α]20/D 77.0 to 82.0°, c = 1-10% (w/v) in water

technique(s)

HPLC: suitable

color

white to off-white

mp

193-196 °C (lit.)

solubility

water: 100 mg/mL, clear, colorless

storage temp.

15-25°C

SMILES string

CO[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O

InChI

1S/C7H14O6/c1-12-7-6(11)5(10)4(9)3(2-8)13-7/h3-11H,2H2,1H3/t3-,4-,5+,6+,7+/m1/s1

InChI key

HOVAGTYPODGVJG-VEIUFWFVSA-N

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Dieser Artikel
67770462711M1379
assay

≥99.0% (HPLC)

assay

≥99.0% (sum of enantiomers, HPLC)

assay

≥99% (TLC)

assay

≥99% (TLC)

technique(s)

HPLC: suitable

technique(s)

-

technique(s)

-

technique(s)

thin layer chromatography (TLC): suitable

Quality Level

300

Quality Level

200

Quality Level

300

Quality Level

200

solubility

water: 100 mg/mL, clear, colorless

solubility

H2O: 0.1 g/mL, clear, colorless

solubility

water: soluble

solubility

water: 50 mg/mL, clear, colorless

form

powder

form

powder

form

solid

form

powder or crystals

storage temp.

15-25°C

storage temp.

-

storage temp.

10-30°C

storage temp.

2-8°C

General description

Methylα-D-mannopyranosid ist ein kompetitiver Inhibitor der Bindung von Mannose durch Escherichia coli. [1]

Application

Methylα-D-mannopyranosid wurde verwendet, um eine Reihe von tri- und tetrahydroxylierten siebengliedrigen Iminozuckern in einer Studie zu synthetisieren, die an einem stabilen Noeuromycin-Analogon mit einer D-Mannokonfiguration arbeitete. [2] Es wurde außerdem in einer Studie zur Untersuchung der primären Mannose-Bindungsstelle von Pradimicin A verwendet. [3]

Other Notes

Für einen umfassenden Überblick über unser vielfältiges Angebot an Monosacchariden für Ihre Forschung empfehlen wir Ihnen den Besuch unserer Seite zur Kategorie Kohlenhydrate.

Lagerklasse

11 - Combustible Solids

wgk

WGK 3

flash_point_f

404.1 °F

flash_point_c

206.74 °C

ppe

Eyeshields, Gloves, type N95 (US)


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Analysenzertifikate (COA)

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Yu Nakagawa et al.
Journal of the American Chemical Society, 133(43), 17485-17493 (2011-09-29)
Pradimicin A (PRM-A) is an actinomycete-derived antibiotic with the lectin-like property of being able to recognize D-mannopyranoside (Man) in the presence of Ca(2+) ion. PRM-A and its derivatives have been attracting a great deal of attention as the only family
M Aronson et al.
The Journal of infectious diseases, 139(3), 329-332 (1979-03-01)
Methyl alpha-D-mannopyranoside (alpha MM), a competitor inhibitor of the binding of mannose by Escherichia coli, was tested for its ability to prevent infection of the urinary tract of mice with infective strains of the organisms. Injection of the bacteria in
Julia Deschamp et al.
Bioorganic & medicinal chemistry, 20(2), 641-649 (2010-10-26)
Noeuromycin is a highly potent albeit unstable glycosidase inhibitor due to its hemiaminal function. While stable D-gluco-like analogs have been reported, no data are available for D-manno-like structures. A series of tri- and tetrahydroxylated seven-membered iminosugars displaying either a D-manno-or
Oliver Schwardt et al.
Bioorganic & medicinal chemistry, 19(21), 6454-6473 (2011-10-04)
Urinary tract infection (UTI) caused by uropathogenic Escherichia coli (UPEC) is one of the most prevalent infectious diseases. Particularly affected are women, who have a 40-50% risk to experience at least one symptomatic UTI episode at some time during their
Karen T Welch et al.
Bioorganic & medicinal chemistry letters, 18(24), 6573-6575 (2008-11-08)
A virtual screening approach was used to identify new glycomimetics. The National Cancer Institute Diversity Set was docked into the carbohydrate binding site of the lectin concanavalin A (ConA). The resulting poses were analyzed and 19 molecules were tested for

Global Trade Item Number

SKUGTIN
M6882-100G04061834061373
M6882-25G04061822703704
M6882-500G04061834061380

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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