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G5755

Gly-Gly-Gly-Gly-Gly

Synonym(e):

Glycyl-glycyl-glycyl-glycyl-glycin, Pentaglycin

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Über diesen Artikel

Lineare Formel:
NH2CH2CO(NHCH2CO)3NHCH2COOH
CAS-Nummer:
Molekulargewicht:
303.27
UNSPSC Code:
12352200
NACRES:
NA.26
PubChem Substance ID:
EC Number:
230-398-3
Beilstein/REAXYS Number:
1716946
MDL number:


assay

≥98% (TLC)

form

solid

color

white

application(s)

peptide synthesis

storage temp.

−20°C

SMILES string

NCC(=O)NCC(=O)NCC(=O)NCC(=O)NCC(O)=O

InChI

1S/C10H17N5O6/c11-1-6(16)12-2-7(17)13-3-8(18)14-4-9(19)15-5-10(20)21/h1-5,11H2,(H,12,16)(H,13,17)(H,14,18)(H,15,19)(H,20,21)

InChI key

MXHCPCSDRGLRER-UHFFFAOYSA-N

Biochem/physiol Actions

Pentaglycine forms interpeptide bridges in peptidogylcan crosslinking and may be used as a tether for markers such as green fluorescent protein (GFP). Pentaglycine may be used as a model peptide in oligoglycine separation technology development.


Lagerklasse

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Christof Renner et al.
Molecular cancer, 9, 2-2 (2010-01-08)
It was previously demonstrated that the dipeptide carnosine inhibits growth of cultured cells isolated from patients with malignant glioma. In the present work we investigated whether carnosine also affects tumor growth in vivo and may therefore be considered for human
Hiroshi Tomoda
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 132(1), 37-44 (2012-01-05)
Methicillin-resistant Staphylococcus aureus (MRSA) is known as a major nosocomial pathogen that has also developed resistance to many antibiotics. Moreover, MRSA resistance to a last-resort antibiotic, vancomycin, has been reported. Therefore, new anti-infectious agents to prevent and treat MRSA infection
Aurelia Delaune et al.
PloS one, 6(2), e17054-e17054 (2011-03-10)
The WalKR two-component system is essential for viability of Staphylococcus aureus, a major pathogen. We have shown that WalKR acts as the master controller of peptidoglycan metabolism, yet none of the identified regulon genes explain its requirement for cell viability.



Global Trade Item Number

SKUGTIN
G5755-25MG04061832777559
G5755-1G04061826682715

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