E6635

Ethylendiamintetraessigsäure Dinatriumsalz Dihydrat

Sigma Grade, suitable for plant cell culture, 98.5-101.5%

• Synonym(e): Dinatriumethylendiamintetraacetat Dihydrat, EDTA Dinatriumsalz, EDTA-Na₂, Edathamil, Edetat Dinatriumsalz Dihydrat, Sequestrene Na₂
• Empirische Formel (Hill-System): C₁₀H₁₄N₂Na₂O₈ · 2H₂O
• CAS-Nummer: 6381-92-6
• Molekulargewicht: 372.24
• Beilstein: 3900609
• EG-Nummer: 205-358-3
• UNSPSC-Code: 12352107
• PubChem Substanz-ID: 24894632
• NACRES: NA.77

Eigenschaften

• Qualität: Sigma Grade
• Assay: 98.5-101.5%
• Form: powder
• Eignung der Reaktion: reagent type: chelator
• Methode(n): cell culture | plant: suitable
• mp (Schmelzpunkt): 248 °C (dec.) (lit.)
• Löslichkeit: H₂O: soluble, clear, colorless
• SMILES String: O.O.O.O.[Na+].[Na+].[Na+].[Na+].OC(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC(O)=O.OC(=O)CN(CCN(CC(O)=O)CC([O-])=O)CC([O-])=O
• InChI: 1S/C10H16N2O8.2Na.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;2*1H2/q;2*+1;;/p-2
• InChIKey: OVBJJZOQPCKUOR-UHFFFAOYSA-L

Beschreibung

Allgemeine Beschreibung

Ethylenediaminetetraacetic acid (EDTA) is an aminopolycarboxylic acid and a hexadentate ligand. It chelates with metal ions, especially with cations to form an octahedral complex. Ethylenediaminetetraacetic acid disodium salt (EDTA) is a blood anticoagulant and contributes to the pathogenesis of pseudothrombocytopenia. It chelates with calcium in the blood and inhibits clotting and is routinely used in haematological tests. It enhances the antibacterial activity of lysozyme. EDTA used in chelation therapy chelates with calcium and favors dilation of artery, solubilisation of atheromatous plaques in atherosclerotic vascular disease. EDTA chelation therapy may also protect from oxidative damage during blood and lipid peroxidation in liver fibrosis.

Anwendung

Ethylenediaminetetraacetic acid disodium salt dihydrate has been in seed germination trials of plant species and in protein extraction from Moss, Physcomitrella paten. It has also been used in lysis and vacuole buffer for the isolation of vacuoles from Petunia petals.

Chelatbildner mit divalenten Kationen. Blockiert Enzyme wie Metallproteasen, die für ihre Aktivität divalente Kationen benötigen.

Sicherheitshinweise

• Piktogramme: GHS08,GHS07
• Signalwort: Warning
• H-Sätze: H332,H373
• P-Sätze: P260 - P271 - P304 + P340 + P312 - P314 - P501
• Gefahreneinstufungen: Acute Tox. 4 Inhalation - STOT RE 2 Inhalation
• Zielorgane: Respiratory Tract
• Lagerklassenschlüssel: 13 - Non Combustible Solids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)