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BP464

Prednisolon

British Pharmacopoeia (BP) Assay Standard

Synonym(e):

1,4-Pregnadien-11β,17α,21-triol-3,20-dion, 1-Dehydrocortisol, 1-Dehydrohydrocortison, 11β,17α,21-Trihydroxy-1,4-pregnadien-3,20-dion

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Über diesen Artikel

Empirische Formel (Hill-System):
C21H28O5
CAS-Nummer:
Molekulargewicht:
360.44
EC Number:
200-021-7
UNSPSC Code:
41116107
NACRES:
NA.24
Beilstein/REAXYS Number:
1354103
MDL number:
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grade

pharmaceutical primary standard

API family

prednisolone

form

crystalline

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

BP

mp

240 °C (dec.) (lit.)

application(s)

pharmaceutical
pharmaceutical small molecule

format

neat

SMILES string

O=C1C=C[C@@]2(C)C(CC[C@]3([H])[C@]2([H])[C@@H](O)C[C@@]4(C)[C@@]3([H])CC[C@]4(O)C(CO)=O)=C1

InChI

1S/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-16,18,22,24,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1

InChI key

OIGNJSKKLXVSLS-VWUMJDOOSA-N

Gene Information

human ... NR3C1(2908)

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Prednisolone BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Estriol Cream
  • Prednisolone Sodium Phosphate Ear Drops
  • Prednisolone Sodium Phosphate Eye Drops
  • Prednisolone Tablets
  • Prednisolone Soluble Tablets
  • Prednisolone Enema
  • Prednisolone Sodium Phosphate Oral Solution
  • Prednisolone Gastro-resistant Tablets
  • Other Notes

    Sales restrictions may apply.

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    Dieser Artikel
    P27000001555005PHR1043
    Prednisolone British Pharmacopoeia (BP) Assay Standard

    BP464

    Prednisolone

    Prednisolone European Pharmacopoeia (EP) Reference Standard

    P2700000

    Prednisolone

    manufacturer/tradename

    BP

    manufacturer/tradename

    EDQM

    manufacturer/tradename

    USP

    manufacturer/tradename

    -

    grade

    pharmaceutical primary standard

    grade

    pharmaceutical primary standard

    grade

    pharmaceutical primary standard

    grade

    certified reference material, pharmaceutical secondary standard

    format

    neat

    format

    neat

    format

    neat

    format

    neat

    shelf life

    limited shelf life, expiry date on the label

    shelf life

    -

    shelf life

    -

    shelf life

    -

    form

    crystalline

    form

    -

    form

    -

    form

    -

    application(s)

    pharmaceutical
    pharmaceutical small molecule

    application(s)

    pharmaceutical (small molecule)

    application(s)

    pharmaceutical (small molecule)

    application(s)

    pharmaceutical (small molecule)


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    pictograms

    Health hazard

    signalword

    Danger

    hcodes

    Hazard Classifications

    Repr. 1B

    Lagerklasse

    6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

    wgk

    WGK 2



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    Ramachandran Venkitaraman et al.
    European urology, 67(4), 673-679 (2014-12-03)
    Prednisolone is widely used as secondary hormonal treatment for castration-resistant prostate cancer (CRPC). We hypothesised that dexamethasone, another corticosteroid, is more active. To compare the activity of prednisolone and dexamethasone in CRPC. This single-centre, randomised, phase 2 trial was performed
    T Bakchoul et al.
    Journal of thrombosis and haemostasis : JTH, 12(6), 871-878 (2014-03-25)
    Heparin, the standard perioperative anticoagulant for the prevention of graft vessel thrombosis in patients undergoing liver transplantation (LT), binds to the chemokine platelet factor 4 (PF4). Antibodies that are formed against the resulting PF4/heparin complexes can induce heparin-induced thrombocytopenia. LT
    Carolien Out et al.
    Journal of hepatology, 61(2), 351-357 (2014-04-01)
    Glucocorticoids, produced by the adrenal gland under control of the hypothalamic-pituitary-adrenal axis, exert their metabolic actions largely via activation of the glucocorticoid receptor (GR). Synthetic glucocorticoids are widely used as anti-inflammatory and immunosuppressive drugs but their application is hampered by



    Global Trade Item Number

    SKUGTIN
    BP46404061835278060

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