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B3916

Boldin

analytical standard

Synonym(e):

2,9-Dihydroxy-1,10-dimethoxy-aporphin

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PackungsgrößeSKUVerfügbarkeitPreis
5 g
Warenkorb auf Verfügbarkeit prüfen
€ 94,50

Über diesen Artikel

Empirische Formel (Hill-System):
C19H21NO4
CAS-Nummer:
Molekulargewicht:
327.37
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
207-509-9
Beilstein/REAXYS Number:
94036
MDL number:

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biological source

plant (Peumus boldus molina)

Quality Level

grade

analytical standard

assay

≥98% (TLC)

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

impurities

≤1% isopropanol

mp

157-164  °C

solubility

ethanol: 50 mg/mL

application(s)

food and beverages
forensics and toxicology
veterinary

format

neat

storage temp.

room temp

SMILES string

COc1cc-2c(CC3N(C)CCc4cc(O)c(OC)c-2c34)cc1O

InChI

1S/C19H21NO4/c1-20-5-4-10-7-15(22)19(24-3)18-12-9-16(23-2)14(21)8-11(12)6-13(20)17(10)18/h7-9,13,21-22H,4-6H2,1-3H3/t13-/m0/s1

InChI key

LZJRNLRASBVRRX-ZDUSSCGKSA-N

General description

Boldine is an aporphine alkaloid isolated from Boldo tree and other plant species. It is a free radical scavenger with anti-inflammatory activity while exhibiting other pharmacological effects such as antidiabetic, antiplatelet aggregation, antipyretic, antinociceptive, antiatherogenic, hepatoprotective and endothelium-protective activity.

Application

Boldine may be used as an analytical reference standard for the quantification of the analyte in biological samples and pharmaceutical preparations using chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

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application(s)

food and beverages
forensics and toxicology
veterinary

application(s)

food and beverages

application(s)

-

application(s)

pharmaceutical (small molecule)

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

-

technique(s)

-

format

neat

format

neat

format

neat

format

neat

Quality Level

100

Quality Level

-

Quality Level

-

Quality Level

-

grade

analytical standard

grade

primary reference standard

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

storage temp.

room temp

storage temp.

-

storage temp.

2-8°C

storage temp.

2-8°C


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pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Lagerklasse

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves



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Analysenzertifikate (COA)

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J Hung et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 59(13), 3177-3183 (2003-10-30)
In this work we present spectroscopic study of Boldine (aporphine alkaloid) that possesses important biological activities, in particular, in interaction with the promastigotes of Leishmania mexicana. The results show the applicability of autofluorescence of this drug to determinate the possible
J Fernández et al.
Phytotherapy research : PTR, 23(7), 1024-1027 (2009-01-16)
Peumus boldus Molina (Monimiaceae), commonly referred to as 'boldo', is used in traditional Chilean medicine to treat hepatic and gastrointestinal diseases. Its leaves are rich in antioxidant compounds, principally alkaloids and flavonoids. This study evaluates the protective effect of a
Yeh-Siang Lau et al.
Experimental biology and medicine (Maywood, N.J.), 237(1), 93-98 (2011-12-14)
Boldine, a major aporphine alkaloid found in Chilean boldo tree, is a potent antioxidant. Oxidative stress plays a detrimental role in the pathogenesis of endothelial dysfunction in hypertension. In the present study, we investigated the effects of boldine on endothelial



Global Trade Item Number

SKUGTIN
B3916-5G04061833429082
B3916-1G04061833429068

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