91897

Phloretin

analytical standard

• Synonym(e): β-(4-Hydroxyphenyl)-2,4,6-trihydroxy-propiophenon, 3-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-1-propanon
• Empirische Formel (Hill-System): C₁₅H₁₄O₅
• CAS-Nummer: 60-82-2
• Molekulargewicht: 274.27
• Beilstein: 1887240
• EG-Nummer: 200-488-7
• MDL-Nummer: MFCD00002288
• UNSPSC-Code: 85151701
• PubChem Substanz-ID: 329770094
• NACRES: NA.24

Eigenschaften

• Qualitätsniveau: 100
• Qualität: analytical standard
• Assay: ≥98.5% (HPLC)
• Haltbarkeit: limited shelf life, expiry date on the label
• Methode(n): HPLC: suitable; gas chromatography (GC): suitable
• Verunreinigungen: ≤8.0% water
• mp (Schmelzpunkt): ~260 °C
• Anwendung(en): cleaning products; cosmetics; flavors and fragrances; food and beverages; personal care
• Format: neat
• Lagertemp.: 2-8°C
• SMILES String: Oc1ccc(CCC(=O)c2c(O)cc(O)cc2O)cc1
• InChI: 1S/C15H14O5/c16-10-4-1-9(2-5-10)3-6-12(18)15-13(19)7-11(17)8-14(15)20/h1-2,4-5,7-8,16-17,19-20H,3,6H2
• InChIKey: VGEREEWJJVICBM-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

Phloretin is a dihydrochalcone flavonoid with antioxidant activity usually found in apples and apple-derived products. It is extensively used for peroxynitrite scavenging and the inhibition of lipid peroxidation.

Major polyphenol found in apple; aglycone of phloridzin.

Anwendung

Phloretin may be used as an internal standard for the determination of sterols and diterpenoids in brown algae using high-performance liquid chromatography (HPLC).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem./physiol. Wirkung

Reacts with vic-dicarbonyl compounds such as glyoxal and methylglyoxal, preventing cytotoxic conjugation with biological macromolecules.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable