46502

Nitrofurantoin

VETRANAL^®, analytical standard

• Synonym(e): N-(5-Nitro-2-furfuryliden)-1-aminohydantoin, Furadantin, Nitrofurantoin
• Empirische Formel (Hill-System): C₈H₆N₄O₅
• CAS-Nummer: 67-20-9
• Molekulargewicht: 238.16
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329757203
• EC Number: 200-646-5
• Beilstein/REAXYS Number: 893207
• MDL number: MFCD00003224

Eigenschaften

• grade: analytical standard
• Quality Segment: 200
• product line: VETRANAL^®
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable, gas chromatography (GC): suitable
• antibiotic activity spectrum: Gram-negative bacteria, Gram-positive bacteria
• application(s): cleaning products; clinical; cosmetics; food and beverages; forensics and toxicology; personal care; pharmaceutical (small molecule)
• format: neat
• mode of action: DNA synthesis | interferes, cell wall synthesis | interferes, protein synthesis | interferes
• SMILES string: [O-][N+](=O)c1ccc(\C=N\N2CC(=O)NC2=O)o1
• InChI: 1S/C8H6N4O5/c13-6-4-11(8(14)10-6)9-3-5-1-2-7(17-5)12(15)16/h1-3H,4H2,(H,10,13,14)/b9-3+
• InChI key: NXFQHRVNIOXGAQ-YCRREMRBSA-N

Beschreibung

General description

Nitrofurantoin is an antibiotic which is effective against both gram-positive and gram-negative bacteria. The drug is primarily used to treat urinary tract infections.

Application

Nitrofurantoin has been used as a reference standard for the determination of nitrofurantoin in milk by high-performance liquid chromatography with electrochemical detection.[1]

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• pictograms: GHS08,GHS07
• signalword: Danger
• hcodes: H302,H317,H334
• pcodes: P261 - P264 - P280 - P301 + P312 - P302 + P352 - P304 + P340 + P312
• Hazard Classifications: Acute Tox. 4 Oral - Resp. Sens. 1 - Skin Sens. 1
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 1
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves