32463

5-Hydroxyflunixin

VETRANAL^®, analytical standard

• Synonym(e): 5-Hydroxy-2-(2-methyl-3-trifluormethylanilino)-nicotinsäure, 5-Hydroxy-2-{[2-methyl-3-(trifluormethyl)-phenyl]-amino}-3-pyridincarbonsäure
• Empirische Formel (Hill-System): C₁₄H₁₁F₃N₂O₃
• CAS-Nummer: 75369-61-8
• Molekulargewicht: 312.24
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329754226
• MDL number: MFCD18252567
• Beilstein/REAXYS Number: 9575875

Eigenschaften

• grade: analytical standard
• Quality Level: 100
• product line: VETRANAL^®
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable, gas chromatography (GC): suitable
• application(s): forensics and toxicology; pharmaceutical (small molecule)
• format: neat
• SMILES string: Cc1c(Nc2ncc(O)cc2C(O)=O)cccc1C(F)(F)F
• InChI: 1S/C14H11F3N2O3/c1-7-10(14(15,16)17)3-2-4-11(7)19-12-9(13(21)22)5-8(20)6-18-12/h2-6,20H,1H3,(H,18,19)(H,21,22)
• InChI key: JSXNJGKWSWRIGA-UHFFFAOYSA-N

Beschreibung

General description

Flunixin (FLU) is a non-steroidal anti-inflammatory drug (NSAID). It is a nicotinic acid derivative, and is involved in inhibiting the enzyme cyclooxygenase in the arachidonic acid cascade. It is anti-pyretic and non-narcotic analgesic in nature, and finds application in veterinary medicine, where it is used to treat a wide variety of disorder in diverse species. This drug can be used to reduce pain and inflammation associated with colic in horses, musculoskeletal disorders, and infectious diseases in cattle. It can also be used as an aid in the treatment of mastitis-metritis-agalactia syndrome in sows. 5-hydroxyflunixin (5OHFLU) is the main metabolite of Flunixin (FLU).

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• pcodes: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3