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32097

Etoricoxib

VETRANAL®, analytical standard

Synonym(e):

5-Chlor-3-[4-(methylsulfonyl)-phenyl]-2-(2-methyl-5-pyridinyl)-pyridin, 5-Chlor-6′-methyl-3-[4-(methylsulfonyl)-phenyl]-2,3′-bipyridin

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PackungsgrößeSKUVerfügbarkeitPreis
25 mg
Warenkorb auf Verfügbarkeit prüfen
€ 95,40

Über diesen Artikel

Empirische Formel (Hill-System):
C18H15ClN2O2S
CAS-Nummer:
Molekulargewicht:
358.84
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
8073797

€ 95,40


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grade

analytical standard

Quality Segment

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

storage temp.

2-8°C

SMILES string

CC1=NC=C(C2=C(C3=CC=C(S(C)(=O)=O)C=C3)C=C(Cl)C=N2)C=C1

InChI

1S/C18H15ClN2O2S/c1-12-3-4-14(10-20-12)18-17(9-15(19)11-21-18)13-5-7-16(8-6-13)24(2,22)23/h3-11H,1-2H3

InChI key

MNJVRJDLRVPLFE-UHFFFAOYSA-N

Gene Information

human ... PTGS2(5743)

General description

Etoricoxib is a non-steroidal cyclooxygenase-2 (COX-2) selective anti-inflammatory drug mostly used to treat patients suffering from osteoarthritis and rheumatoid arthritis.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Etoricoxib may have been used as reference standard in liquid chromatography-tandem mass spectrometry method with atmospheric pressure chemical ionization (LC-APCI/MS/MS) method for determination of etoricoxib from human plasma.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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Dieser Artikel
O5879PHR1059SML3271
technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

grade

analytical standard

grade

analytical standard

grade

certified reference material, pharmaceutical secondary standard

grade

-

format

neat

format

neat

format

neat

format

-

storage temp.

2-8°C

storage temp.

-

storage temp.

2-8°C

storage temp.

2-8°C

Gene Information

human ... PTGS2(5743)

Gene Information

-

Gene Information

human ... ATP4A(495), ATP4B(496)

Gene Information

-

Quality Level

100

Quality Level

200

Quality Level

300

Quality Level

100


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pictograms

Skull and crossbones

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 2 Dermal - Acute Tox. 4 Oral

Lagerklasse

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3



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Paola Patrignani et al.
Expert opinion on pharmacotherapy, 4(2), 265-284 (2003-02-04)
The development of COX2 inhibitors with improved biochemical selectivity (such as etoricoxib and valdecoxib) over that of commercially available coxibs has been driven by the potential advantage of safety using higher coxib doses for increased efficacy. Etoricoxib has been approved
Rik J Lories
Expert opinion on drug metabolism & toxicology, 8(12), 1599-1608 (2012-11-07)
Nonsteroidal anti-inflammatory drugs (NSAIDs) are first-line therapies in the management of patients with ankylosing spondylitis. This chronic inflammatory skeletal disorder, a subtype of spondyloarthritis, is characterized by inflammatory back pain and affects young adults causing important suffering and disability. Long-term
Determination of etoricoxib in human plasma using automated on-line solid-phase extraction coupled with LC-APCI/MS/MS.
Dalmora, Sergio Luiz, et al.
Quimica nova, 31.3, 574-578 (2008)



Global Trade Item Number

SKUGTIN
32097-25MG04061826702130

Questions

  1. Does Etoricoxib VETRANAL®, analytical standard are traceable to the CRM?

    1 answer
    1. Product 32097-25MG, Etoricoxib, VETRANAL®, analytical standard, is not a Certified Reference Material and is not traceable to a Certified Reference Material. This product is a reference standard that is not certified. However, it can be used for forensics, toxicology, pharmaceutical (small molecule), and veterinary applications.

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