14690

Bis(cyclohexanon)oxaldihydrazon

for spectrophotometric det. of Cu, ≥99.0%

• Synonym(e): Cuprizon, Oxalsäure-bis-(cyclohexylidenhydrazid)
• Empirische Formel (Hill-System): C₁₄H₂₂N₄O₂
• CAS-Nummer: 370-81-0
• Molekulargewicht: 278.35
• UNSPSC Code: 41116105
• NACRES: NA.21
• PubChem Substance ID: 329750579
• EC Number: 206-729-2
• Beilstein/REAXYS Number: 2388004
• MDL number: MFCD00001659

Eigenschaften

• Quality Segment: 100
• assay: ≥99.0% (N), ≥99.0%
• form: powder
• quality: for spectrophotometric det. of Cu
• technique(s): UV/Vis spectroscopy: suitable
• mp: 210-214 °C
• SMILES string: O=C(N\N=C1\CCCCC1)C(=O)N\N=C2/CCCCC2
• InChI: 1S/C14H22N4O2/c19-13(17-15-11-7-3-1-4-8-11)14(20)18-16-12-9-5-2-6-10-12/h1-10H2,(H,17,19)(H,18,20)
• InChI key: DSRJIHMZAQEUJV-UHFFFAOYSA-N

Beschreibung

General description

Cuprizone (Bis(cyclohexanone)oxaldihydrazone) is a physically unstable compound and is a well-known neurotoxic agent.

Application

Cuprizone (Bis(cyclohexanone)oxaldihydrazone) was used for toxic demyelination in the central nervous system in order to investigate the pathobiology of remyelination in the corpus callosum, so as to study the human demyelinating diseases such as multiple sclerosis. It was also used a model to study components of neuroinflammation.

Other Notes

In der Gegenwart eines Kupfersalzes, katalysiert dieser Ligand Ullmann-Typ C-N bindungsbildende Reaktionen unter milden, wässrigen Bedingungen.

Für die spektrophotometrische Bestimmung von Cu(II)

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)