MAB5404
Anti-Nitrotyrosin-Antikörper, Klon 2A8.2
clone 2A8.2, Chemicon®, from mouse
Größe auswählen
| Packungsgröße | SKU | Verfügbarkeit | Preis |
|---|---|---|---|
| 100 μg | Warenkorb auf Verfügbarkeit prüfen | € 452,00 |
Über diesen Artikel
biological source
mouse
Quality Level
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
2A8.2, monoclonal
species reactivity (predicted by homology)
all
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable (paraffin), western blot: suitable
isotype
IgG2b
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... NOS1(4842)
General description
Immunogen
Application
Neurowissenschaft
Oxidativer Stress
1:50–1:100 einer früheren Charge an paraffineingebettetem, mit 10 % neutral gepuffertem Formalin fixiertem Lebergewebe der Maus (Tier behandelt mit Zymosan) und normalem menschlichem Kleinhirngewebe. Die Gewebe müssen mit hitzeinduzierter Epitopgewinnung (HIER) vorbehandelt werden. Die Inkubationszeit mit MAB5404 betrug 10 Minuten, und die Reaktion wurde mit dem Chemicon IHC-Select HRP/DAB-Kit (Art.-Nr. DAB150) entwickelt.
Optimale Arbeitsverdünnungen müssen vom Endanwender bestimmt werden.
Biochem/physiol Actions
Physical form
Preparation Note
Analysis Note
Western-Blot-Analyse:
Eine 1:500-Verdünnung dieses Antikörpers wies Nitrotyrosin auf 10 μg Nitrotyrosin-Immunblot-Kontrollen nach (Art.-Nr. 12-354).
Nitriertes BSA
Other Notes
Legal Information
Disclaimer
1 of 1
Dieser Artikel | |||
|---|---|---|---|
| clone 2A8.2, monoclonal | clone polyclonal | clone 39B6, monoclonal | clone EM-30, monoclonal |
| Gene Information human ... NOS1(4842) | Gene Information human ... NOS1(4842) | Gene Information human ... NOS1(4842) | Gene Information - |
| biological source mouse | biological source rabbit | biological source mouse | biological source mouse |
| antibody form purified immunoglobulin | antibody form affinity isolated antibody | antibody form purified immunoglobulin | antibody form purified immunoglobulin |
| isotype IgG2b | isotype - | isotype IgG2a | isotype - |
| Quality Level 100 | Quality Level 200 | Quality Level 100 | Quality Level - |
Still not finding the right product?
Probieren Sie unser Produkt-Auswahlhilfe, um Ihre Auswahl einzugrenzen
Lagerklasse
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Analysenzertifikate (COA)
Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.
Besitzen Sie dieses Produkt bereits?
In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.
Verwandter Inhalt
"Redox reactions are powerful chemical processes that involve the reduction and oxidation of proteins and metabolites found in living things. The mechanisms that regulate them are key to maintaining homeostasis and the balance between good health and disease pathology. Oxidative stress is the state where the delicate balance of redox biology is upset, and the pathology of oxidative stress are the cellular consequences to such an imbalance."
"Aging: getting older, exhibiting the signs of age, the decline in the physical (and mental) well-being over time, leading to death. Since the beginning of time, man has been obsessed with trying to slow down, stop, or even reverse the signs of aging. Many have gone as far as experimenting with nutritional regimens, eccentric exercises, fantastic rituals, and naturally occurring or synthetic wonder-elements to evade the signs of normal aging. Biologically speaking, what is aging? And what does the latest research tell us about the possibility of discovering the elusive “fountain of youth”? Many advances in our understanding of aging have come from systematic scientific research, and perhaps it holds the key to immortality. Scientifically, aging can be defined as a systems-wide decline in organismal function that occurs over time. This decline occurs as a result of numerous events in the organism, and these events can be classified into nine “hallmarks” of aging, as proposed by López-Otin et al. (2013). Several of the pathologies associated with aging are a direct result of these events going to extremes and may also involve aberrant activation of proliferation signals or hyperactivity. The hallmarks of aging have been defined based on their fulfillment of specific aging related criteria, such as manifestation during normal aging, acceleration of aging if experimentally induced or aggravated, and retardation of aging if prevented or blocked, resulting in increased lifespan. The nine hallmarks of aging are genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, deregulated nutrient sensing, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, and altered intercellular communication. The biological processes underlying aging are complex. By understanding the hallmarks in greater detail, we can get closer to developing intervention strategies that can make the aging process less of a decline, and more of a recline."
Global Trade Item Number
| SKU | GTIN |
|---|---|
| MAB5404 | 04053252467530 |