AB15514

Anti-Neuroligin 3 Antibody

Chemicon^®, from rabbit

• UNSPSC Code: 12352203
• NACRES: NA.41
• eCl@ss: 32160702
• Conjugate: unconjugated
• Clone: polyclonal
• Application: ELISA, IHC, WB
• Citations: -

Eigenschaften

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: purified antibody
• antibody product type: primary antibodies
• clone: polyclonal
• species reactivity: human
• manufacturer/tradename: Chemicon^®
• technique(s): ELISA: suitable, immunohistochemistry: suitable, western blot: suitable
• NCBI accession no.: NM_018977.2
• UniProt accession no.: Q9NZ94
• shipped in: dry ice
• target post-translational modification: unmodified
• Gene Information: human ... NLGN3(54413)

Beschreibung

General description

Neuroligins are Type I membrane proteins enriched in synaptic plasma membranes and clustered in synaptic clefts and postsynaptic densities. They have been characterized as neuronal cell surface proteins and are thought to be involved in cell-cell-interactions by forming intercellular junctions through binding to beta-neurexins. They play a major role in the formation or maintenance of synaptic junctions. They are also thought to be involved in the specification of excitatory synapses. Neuroligins interact with beta-neurexins and this interaction is involved in the formation of functional synapses.

Immunogen

Synthetic peptide near the C-terminus of human Neuroligin 3

Application

Research Category
Neuroscience

Research Sub Category
Synapse & Synaptic Biology

This Anti-Neuroligin 3 Antibody is validated for use in WB, IH, ELISA for the detection of Neuroligin 3.

Western blot: 1-10 μg/mL using ECL.
Immunohistochemistry: Not tested. It is recommended that the antibody be tried at 2-20 μg/mL
ELISA: 1:10,000-1:100,000 using 50-100 ng of control peptide/well.
Optimal working dilutions must be determined by end user.

Biochem/physiol Actions

Neuroligin 3 (NLGN3)

Physical form

Format: Purified

Liquid in PBS with 0.1% BSA and 0.05% sodium azide

Preparation Note

Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklasse: 12 - Non Combustible Liquids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable