575003-M

α-Synuclein A53T, Human, Recombinant, E. coli

• NACRES: NA.77
• UNSPSC Code: 12352202
• Form: liquid
• Assay: ≥95% (SDS-PAGE)

Eigenschaften

• assay: ≥95% (SDS-PAGE)
• Quality Segment: 100
• form: liquid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze, avoid repeated freeze/thaw cycles
• storage temp.: −20°C

Beschreibung

General description

Recombinant, human α-synuclein containing an A53T mutation and expressed in E. coli. α-synuclein is an acidic neuronal protein of 140 amino acids that has been implicated in the pathogenesis of Parkinson′s disease and related neurodegenerative disorders. α-Synuclein (A53T) is a point mutant of the α-synuclein gene that has been linked to autosomal dominant early onset Parkinson′s Disease (PD). The apparent molecular weight on SDS-PAGE is ~19-20 kDa.

Physical form

In 100 mM NaCl, 20 mM Tris-HCl, pH 7.5.

Preparation Note

Following initial thaw, aliquot and freeze (-20°C).

Other Notes

Lashuel, H.A., et al. 2002. J. Mol. Biol.322, 1089.
Park, S.M., et al. 2002. Blood100, 2506.
Polymeropoulos, M.H., et al. 1997. Science276, 2045.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Sicherheitshinweise

• Lagerklasse: 10 - Combustible liquids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable