14-521

Arg Protein, active, human, 10 µg

• UNSPSC-Code: 12352202
• eCl@ss: 32160405

Eigenschaften

• Beschreibung: protein target Arg
• Qualitätsniveau: 100
• Aufgereinigt durch: (Ni²⁺/NTA-agarose)
• Methode(n): activity assay: suitable
• UniProt-Hinterlegungsnummer: P42684
• Angaben zum Gen: human ... ABL2(27)

Beschreibung

Allgemeine Beschreibung

FUNCTION: SwissProt: P42684 # Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics.
COFACTOR: Magnesium or manganese.
SIZE: 1182 amino acids; 128343 Da
SUBCELLULAR LOCATION: Cytoplasm.
TISSUE SPECIFICITY: Widely expressed.
PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.
SIMILARITY: SwissProt: P42684 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. ABL subfamily. & Contains 1 protein kinase domain. & Contains 1 SH2 domain. & Contains 1 SH3 domain.

Qualität

Routinely evaluated by phosphorylation of Abltide.

Physikalische Eigenschaften

121.9 kDa

Lagerung und Haltbarkeit

6 months at -70°C

Hinweis zur Analyse

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H317
• P-Sätze: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Gefahreneinstufungen: Skin Sens. 1
• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable