104662

Cellvento^® ModiFeed Sial+ COMP

Chemically defined cell culture feed - EMPROVE^® CCM, compacted dry powder

• UNSPSC Code: 41106213

Eigenschaften

• Quality Segment: 500
• description: shipped with cooling packs
• product line: Cellvento^®
• form: dry powder
• greener alternative product characteristics: Design for Energy Efficiency; Learn more about the Principles of Green Chemistry.
• sustainability: Greener Alternative Product
• technique(s): cell culture | mammalian: suitable
• application(s): pharma/biopharma processes
• greener alternative category: DfS-Developed
• storage temp.: 2-8°C

Beschreibung

General description

Cellvento^® ModiFeed Sial+ COMP is part of the ModiFeed platform. It is a highly concentrated, one-part, pH neutral feed added to replenish depleted nutrients required for cellular function and to extend the production phase in fed-batch mode, while simultanously maximizing sialylation on the protein of interest. It is recommended combination with the production media Cellvento^® 4CHO and EX-CELL^® Advanced CHO or other production media.

We are committed to bringing you Greener Alternative Products, which belongs to one of the four categories of greener alternatives. This product is a Design for Sustainability (DfS) developed product. Click here to view its DfS scorecard.

Application

Control of protein glycosylation, such as sialylation, while maximizing productivity is key for successful therapeutic protein development and production. N-glycoslyations of IgG Fc, particularly sialylation, has been reported to exert significant anti-inflammatory effects. High sialylation levels can help to increase stability, safety, and efficacy of the protein of interest. Cellvento^® ModiFeed Sial+ COMP was developed to increase sialylation while maintaining or improving titer in CHO fed-batch processes

Features and Benefits

• Reduced complexity in fed-batch process
• Complete feed maximizing galactosylation
• Highly concentrated to reduce required feed volume
• Compacted format for conventient handling
• Higher liquid feed stability at room temperature

Preparation Note

Formulated to contain 155.8 grams of powder per liter of feed.

Legal Information

CELLVENTO is a registered trademark of Merck KGaA, Darmstadt, Germany

EX-CELL is a registered trademark of Merck KGaA, Darmstadt, Germany

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3