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Merck
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Dokumente

07-394

Sigma-Aldrich

Anti-MAGE-D1/NRAGE Antibody

serum, Upstate®

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

100

Antikörperform

serum

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Speziesreaktivität

rat, mouse, human

Hersteller/Markenname

Upstate®

Methode(n)

immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

Isotyp

IgG

NCBI-Hinterlegungsnummer

NM_006986

UniProt-Hinterlegungsnummer

Q9Y5V3

Versandbedingung

dry ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... MAGED1(9500)

Spezifität

NRAGE/MAGE-D1

Immunogen

GST fusion protein corresponding to residues 53-295 of rat MAGE-D1/NRAGE

Anwendung

Research Category
Neurowissenschaft
Research Sub Category
Neurodegenerative Krankheiten

Entwicklungsneurowissenschaft
Anti-MAGE-D1/NRAGE Antibody is an antibody against MAGE-D1/NRAGE for use in IP, WB, IH.

Qualität

routinely evaluated by immunoblot in RIPA lysates from PC12 cells

Zielbeschreibung

90-96 kDa

Physikalische Form

Antiserum
0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide, before the addition of glycerol to 30%

Lagerung und Haltbarkeit

2 years at -20°C

Rechtliche Hinweise

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 2

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

Amir H Salehi et al.
The Journal of biological chemistry, 277(50), 48043-48050 (2002-10-12)
The p75 neurotrophin receptor (p75NTR) mediates signaling events leading to activation of the JNK pathway and cell death in a variety of cell types. We recently identified NRAGE, a protein that directly interacts with the p75NTR cytosolic region and facilitates
A H Salehi et al.
Neuron, 27(2), 279-288 (2000-09-14)
The mechanisms employed by the p75 neurotrophin receptor (p75NTR) to mediate neurotrophin-dependent apoptosis are poorly defined. Two-hybrid analyses were used to identify proteins involved in p75NTR apoptotic signaling, and a p75NTR binding partner termed NRAGE (for neurotrophin receptor-interacting MAGE homolog)
Jennifer M Doyle et al.
Molecular cell, 39(6), 963-974 (2010-09-25)
The melanoma antigen (MAGE) family consists of more than 60 genes, many of which are cancer-testis antigens that are highly expressed in cancer and play a critical role in tumorigenesis. However, the biochemical and cellular functions of this enigmatic family

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