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938882

Sigma-Aldrich

NanoFabTx Polymers for Microneedles

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Hyaluronic acid sodium salt

Synonym(e):

Hyaluronic acid sodium salt

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About This Item

Lineare Formel:
(C14H21NaNO11)n
CAS-Nummer:

Qualitätsniveau

Assay

≥90%

Mol-Gew.

100-150 kDa

Lagertemp.

2-8°C

SMILES String

O[C@H]1[C@H](O[C@@H]2O[C@H](C(O[Na])=O)[C@@H](OC)[C@H](O)[C@H]2O)[C@@H](NC(C)=O)[C@H](C)O[C@@H]1CO

Anwendung

NanoFabTx Polymers for Microneedles are carefully selected polymers that can be used to formulate microneedle patches. Microneedles are tiny projections of needles approximately 400-800um in length arranged in a small 1cm x 1cm patch. Microneedles are composed of blends of synthetic or natural polymers at suitable concentrations. Sodium hyaluronic acid (HA) is the derivate of a natural polymer and is a natural polysaccharide. It is a water-soluble polymer and is available in different molecular weights. The formation of the microneedles depends on the molecular weight and concentration of HA.


The NanoFabTx Polymers for Microneedles can be used with the microneedle templates to formulate microneedle that can be used for several applications, such as delivering various therapeutic molecules and vaccine antigens via the skin. The selected polymer will enable users to:

1)save time in selecting the polymer and provide a starting point to formulate microneedles by avoiding lengthy trial-and-error optimization.

2)formulate microneedles for various drug delivery applications.

Rechtliche Hinweise

NANOFABTX is a trademark of Sigma-Aldrich Co. LLC

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Microneedle arrays as transdermal and intradermal drug delivery systems: Materials science, manufacture and commercial development
Larra?eta E, et al.
Materials Science & Engineering. R, Reports : A Review Journal, 104, 1-32 (2016)
A dual-delivery platform for vaccination using antigen-loaded nanoparticles in dissolving microneedles
Gomes K B, et al.
International Journal of Pharmaceutics, 613, 121393-121393 (2022)
Keegan Braz Gomes et al.
International journal of pharmaceutics, 613, 121393-121393 (2021-12-21)
Effective vaccines delivered via painless methods would revolutionize the way people approach vaccinations. This study focused on the development of fast-dissolving microneedles (MNs) to deliver antigen-loaded sustained release polymeric nanoparticles (NPs), achieving a dual-delivery platform for vaccination through the skin.

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

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