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860581
α-Methyl-α-Phenylsuccinimid
99%
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About This Item
Empirische Formel (Hill-System):
C11H11NO2
CAS-Nummer:
Molekulargewicht:
189.21
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352100
PubChem Substanz-ID:
NACRES:
NA.22
Empfohlene Produkte
Assay
99%
Form
solid
mp (Schmelzpunkt)
83-85 °C (lit.)
Funktionelle Gruppe
phenyl
SMILES String
CC1(CC(=O)NC1=O)c2ccccc2
InChI
1S/C11H11NO2/c1-11(7-9(13)12-10(11)14)8-5-3-2-4-6-8/h2-6H,7H2,1H3,(H,12,13,14)
InChIKey
UDESUGJZUFALAM-UHFFFAOYSA-N
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
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J C Gomora et al.
Molecular pharmacology, 60(5), 1121-1132 (2001-10-20)
Inhibition of T-type Ca(2+) channels has been proposed to play a role in the therapeutic action of succinimide antiepileptic drugs. Despite the widespread acceptance of this hypothesis, recent studies using rat and cat neurons have failed to confirm inhibition of
Arcadius V Krivoshein
ACS chemical neuroscience, 7(3), 316-326 (2016-01-08)
Although the antiepileptic properties of α-substituted lactams, acetamides, and cyclic imides have been known for over 60 years, the mechanism by which they act remains unclear. I report here that these compounds bind to the nicotinic acetylcholine receptor (nAChR) and
J M Streete et al.
Therapeutic drug monitoring, 17(3), 280-286 (1995-06-01)
Analysis of desmethylmethsuximide by high-performance liquid chromatography (HPLC) is described. After adding an internal standard (IS), 200 microliters of plasma was buffered to pH 4.5 and extracted with dichloroethane. The organic solvent was then evaporated to dryness and the residue
D A Coulter et al.
British journal of pharmacology, 100(4), 807-813 (1990-08-01)
1. Currents evoked by applications of gamma-aminobutyric acid (GABA) to acutely dissociated thalamic neurones were analysed by voltage-clamp techniques, and the effects of the anticonvulsant succinimides ethosuximide (ES) and alpha-methyl-alpha-phenylsuccinimide (MPS) and the convulsants tetramethylsuccinimide (TMS), picrotoxin, pentylenetetrazol (PTZ), and
Pharmacokinetics of N-desmethylmethsuximide in pediatric patients.
M V Miles et al.
The Journal of pediatrics, 114(4 Pt 1), 647-650 (1989-04-01)
Chromatograms
application for HPLCapplication for HPLCActive Filters
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