855774

Colchicin

95%

• Synonym(e): (S)-N-(5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)acetamid
• Empirische Formel (Hill-System): C₂₂H₂₅NO₆
• CAS-Nummer: 64-86-8
• Molekulargewicht: 399.44
• EC Number: 200-598-5
• UNSPSC Code: 12352103
• MDL number: MFCD00078484
• Beilstein/REAXYS Number: 2228813

Eigenschaften

• assay: 95%
• optical activity: [α]24/D −443°, c = 1.7 in H₂O
• impurities: 10% ethyl acetate and chloroform
• mp: 150-160 °C (dec.) (lit.)
• SMILES string: COC1=CC=C2C(=CC1=O)[C@H](CCc3cc(OC)c(OC)c(OC)c23)NC(C)=O
• InChI: 1S/C22H25NO6/c1-12(24)23-16-8-6-13-10-19(27-3)21(28-4)22(29-5)20(13)14-7-9-18(26-2)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24)/t16-/m0/s1
• InChI key: IAKHMKGGTNLKSZ-INIZCTEOSA-N

Beschreibung

Application

For a review summarizing the metabolism and pharmacokinetics of this alkaloid, see Z. Gastroenterol. .

Sicherheitshinweise

• pictograms: GHS06,GHS08
• signalword: Danger
• hcodes: H300,H340
• pcodes: P202 - P264 - P270 - P280 - P301 + P310 - P405
• Hazard Classifications: Acute Tox. 2 Oral - Muta. 1B
• Lagerklasse: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges