548081

2,4-Difluorbenzolsulfonylchlorid

97%

• Lineare Formel: F₂C₆H₃SO₂Cl
• CAS-Nummer: 13918-92-8
• Molekulargewicht: 212.60
• MDL-Nummer: MFCD00042481
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24879012
• NACRES: NA.22

Eigenschaften

• Assay: 97%
• Brechungsindex: n20/D 1.518 (lit.)
• bp: 236-237 °C (lit.)
• Dichte: 1.581 g/mL at 25 °C (lit.)
• SMILES String: Fc1ccc(c(F)c1)S(Cl)(=O)=O
• InChI: 1S/C6H3ClF2O2S/c7-12(10,11)6-2-1-4(8)3-5(6)9/h1-3H
• InChIKey: FJSAJUXIHJIAMD-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

2,4-Difluorobenzenesulfonyl chloride is an aryl sulfonyl chloride derivative.

Anwendung

2,4-Difluorobenzenesulfonyl chloride may be used in the preparation of 2,4-difluoro-N,N-dimethylbenzenesulfonamide, a precursor for poly(aryl ether sulfonamide)s.
It may be used in the preparation of the following benzenesulfonamide quinoline derivatives with potent anti-HIV-1 (human immunodeficiency virus type 1) activity:

• 2,4-difluoro-N-methyl-N-(quinolin-8-yl)benzenesulfonamide
• N-ethyl-2,4-difluoro-N-(quinolin-8-yl)benzenesulfonamide
• 2,4-difluoro-N-(quinolin-8-yl)benzenesulfonamide

Sicherheitshinweise

• Piktogramme: GHS05
• Signalwort: Danger
• H-Sätze: H314
• P-Sätze: P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363 - P405
• Gefahreneinstufungen: Eye Dam. 1 - Skin Corr. 1B
• Lagerklassenschlüssel: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): 230.0 °F - closed cup
• Flammpunkt (°C): 110 °C - closed cup
• Persönliche Schutzausrüstung: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter