- Nickel-catalyzed cross-coupling of non-activated and functionalized alkyl halides with alkyl Grignard reagents.
Nickel-catalyzed cross-coupling of non-activated and functionalized alkyl halides with alkyl Grignard reagents.
Angewandte Chemie (International ed. in English) (2009-01-29)
Oleg Vechorkin, Xile Hu
PMID19173360
ABSTRACT
Reacting in the 'Ni'ck of time: The title reaction is realized by using an isolated Ni(II) complex (1). The catalysis tolerates a wide range of important functional groups that are often incompatible with Grignard reagents in cross-coupling reactions.
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