- Metal-free, highly efficient organocatalytic amination of benzylic C-H bonds.
Metal-free, highly efficient organocatalytic amination of benzylic C-H bonds.
Chemical communications (Cambridge, England) (2013-03-29)
Qicai Xue, Jin Xie, Huamin Li, Yixiang Cheng, Chengjian Zhu
PMID23536004
ABSTRACT
A new synthetic approach toward direct C-N bond formation through sp(3) C-H activation has been developed under metal-free conditions. Both primary and secondary benzylic C-H substrates could react smoothly with various amines to give only mono-amination products with good to excellent yields.
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