- Gold-catalyzed efficient synthesis of azepan-4-ones via a two-step [5 + 2] annulation.
Gold-catalyzed efficient synthesis of azepan-4-ones via a two-step [5 + 2] annulation.
Chemical communications (Cambridge, England) (2010-05-06)
Li Cui, Longwu Ye, Liming Zhang
PMID20442898
ABSTRACT
A surprisingly efficient synthesis of azepan-4-ones via a two-step [5 + 2] annulation is developed. This reaction involves a key gold catalysis and shows generally high regioselectivities and good to excellent diastereoselectivities.
MATERIALS