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Lamotrigine

Name: Lamotrigine
Brand: USP

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5-diamine, GI 267119X

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About This Item

Empirical Formula (Hill Notation):

C₉H₇Cl₂N₅

CAS Number:

84057-84-1

Molecular Weight:

256.09

NACRES:

NA.24

PubChem Substance ID:

329750224

UNSPSC Code:

41116107

MDL number:

MFCD00865333

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Properties

grade

pharmaceutical primary standard

API family

lamotrigine

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

Nc1nnc(c(N)n1)-c2cccc(Cl)c2Cl

InChI

1S/C9H7Cl2N5/c10-5-3-1-2-4(6(5)11)7-8(12)14-9(13)16-15-7/h1-3H,(H4,12,13,14,16)

InChI key

PYZRQGJRPPTADH-UHFFFAOYSA-N

Gene Information

human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)

Description

Biochem/physiol Actions

Anticonvulsant.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

Other Notes

Sales restrictions may apply.

USP issued SDS can be found here.

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This Item	PHR1392	BP1097	Y0001031
USP 1356756 Lamotrigine	Supelco PHR1392 Lamotrigine	BP1097 Lamotrigine	Y0001031 Lamotrigine for peak identification
grade pharmaceutical primary standard	grade certified reference material, pharmaceutical secondary standard	grade pharmaceutical primary standard	grade pharmaceutical primary standard
manufacturer/tradename USP	manufacturer/tradename -	manufacturer/tradename BP	manufacturer/tradename EDQM
format neat	format neat	format neat	format neat
application(s) pharmaceutical (small molecule)	application(s) pharmaceutical (small molecule)	application(s) pharmaceutical pharmaceutical small molecule	application(s) pharmaceutical (small molecule)
API family lamotrigine	API family lamotrigine	API family lamotrigine	API family lamotrigine
Gene Information human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)	Gene Information human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)	Gene Information human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)	Gene Information human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)

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pictograms

GHS06

signalword

Danger

hcodes

H301

pcodes

P264 - P270 - P301 + P310 - P405 - P501

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

flash_point_f

Not applicable

flash_point_c

Not applicable

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Effect of Permeation enhancers on diffusion of lamotrigine drug through cellophane membrane.

Rao, Vinay, et al.

American Journal of Advanced Drug Delivery, 1.4, 606-610 (2013)

Beneficial effects of mood stabilizers lithium, valproate and lamotrigine in experimental stroke models.

Zhi-fei Wang et al.

Acta pharmacologica Sinica, 32(12), 1433-1445 (2011-11-08)

The mood stabilizers lithium, valproate and lamotrigine are traditionally used to treat bipolar disorder. However, accumulating evidence suggests that these drugs have broad neuroprotective properties and may therefore be promising therapeutic agents for the treatment of neurodegenerative diseases, including stroke.

Lamotrigine for chronic neuropathic pain and fibromyalgia in adults.

Philip J Wiffen et al.

The Cochrane database of systematic reviews, 12(12), CD006044-CD006044 (2013-12-04)

This is an update of the original Cochrane review entitled Lamotrigine for acute and chronic pain published in Issue 2, 2007, and updated in Issue 2, 2011. Some antiepileptic medicines have a place in the treatment of neuropathic pain (pain

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Global Trade Item Number

SKU	GTIN
1356756-150MG	04061834095187

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