1.04956

tri-Potassium citrate monohydrate

EMPROVE^® ESSENTIAL, Ph. Eur., BP, USP, FCC, E 332

• Synonym(s): tri-Potassium citrate monohydrate, Tripotassium citrate, Citric acid potassium salt, 2-Hydroxy-1,2,3-Propanetriccarboxylic Acid
• Empirical Formula (Hill Notation): C₆H₅K₃O₇ · xH₂O
• CAS Number: 6100-05-6
• Molecular Weight: 306.39 (anhydrous basis)
• MDL number: MFCD00150442
• UNSPSC Code: 12352107
• E Number: E332
• EC Index Number: 212-755-5

Properties

• Agency: BP; Ph. Eur.; USP
• Quality Level: 500
• reg. compliance: FCC
• product line: EMPROVE^® ESSENTIAL
• form: solid
• pH: 7.5-9.0 (20 °C, 50 g/L in H₂O)
• mp: >180 °C (Elimination of water of crystallisation)
• density: 1.98 g/cm³ at 20 °C
• application(s): liquid formulation; ophthalmics; pharmaceutical; semi-solid formulation; solid formulation
• storage temp.: 15-25°C
• InChI: 1S/C6H8O7.3K.H2O/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;;1H2/q;3*+1;/p-3
• InChI key: PJAHUDTUZRZBKM-UHFFFAOYSA-K

Description

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

tri-Potassium citrate is typically used as buffering, alkalizing and sequestering agent. Additional uses include the application as potassium source and as therapeutic ingredient to treat cystitis by alkalizing the urine.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable