L070000

Fast Deprotection Cap A

45-55 g/L (TAC2O content, gravimetric)

• UNSPSC Code: 41116105
• NACRES: NA.21

Properties

• type: for DNA synthesis; for DNA synthesis
• product line: Proligo Reagents
• form: liquid
• storage condition: dry at room temperature
• concentration: 45-55 g/L (TAC2O content, gravimetric)
• color: clear

Description

General description

Fast Deprotection Cap A contains tert-butylphenoxyacetyl aceticanhydride (TAC2O) in tetrahydrofuran, which ensures thedisplacement of tert-butylphenoxyacetyl (TAC) on guanine bases doesnot occur.

Preparation Note

Tetrahydrofurane / TAC₂O 100/5 (v/w)

Other Notes

Fast Deprotection Cap A solution must be used for synthesis with Sigma-Aldrich′s TAC-protected phosphoramidites. Fast Deprotection Cap A solution, containing tert-butylphenoxyacetyl acetic anhydride (TAC₂O) in tetrahydrofuran, is used in place of Cap A solution to ensure that the displacement of tert-butylphenoxyacetyl (TAC) on guanine bases of the TAC-protected DNA and RNA phosphoramidites does not occur.

Safety Information

• Pictograms: GHS02,GHS08,GHS07
• Signal Word: Danger
• Hazard Statements: H225,H319,H335,H336,H351
• Precautionary Statements: P202 - P210 - P233 - P240 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
• Target Organs: Central nervous system, Respiratory system
• Supplementary Hazards: EUH019
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point(F): 6.1 °F
• Flash Point(C): -14.4 °C