G6503

Glycine ethyl ester hydrochloride

99%, for peptide synthesis

• Synonym(s): GEE, Ethyl glycinate hydrochloride
• Linear Formula: NH₂CH₂COOC₂H₅ · HCl
• CAS Number: 623-33-6
• Molecular Weight: 139.58
• Beilstein: 3594034
• EC Number: 210-787-4
• MDL number: MFCD00012871
• UNSPSC Code: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 24895258
• NACRES: NA.22

Properties

• product name: Glycine ethyl ester hydrochloride, 99%
• Assay: 99%
• form: powder or chunks
• reaction suitability: reaction type: solution phase peptide synthesis
• technique(s): drug transporter assay: suitable
• color: white
• mp: 145-146 °C (lit.)
• application(s): peptide synthesis
• SMILES string: Cl.CCOC(=O)CN
• InChI: 1S/C4H9NO2.ClH/c1-2-7-4(6)3-5;/h2-3,5H2,1H3;1H
• InChI key: TXTWXQXDMWILOF-UHFFFAOYSA-N

Description

Application

Glycine ethyl ester (GEE) is used in conjunction with N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide (EDC) for carboxyl-footprinting studies of proteins. The GEE/EDC protocol effects specific derivatization of glutamate and aspartate carboxyl side chains on intact proteins. This reaction is readily done under aqueous conditions at physiological pH.

Safety Information

• Pictograms: GHS05
• Signal Word: Danger
• Hazard Statements: H318
• Precautionary Statements: P280 - P305 + P351 + P338
• Hazard Classifications: Eye Dam. 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves