632732

1-Boc-pyrazole-4-boronic acid pinacol ester

97%

• Synonym(s): 1,1-dimethylethyl ester 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-Pyrazole-1-carboxylic acid, 1-tert-Butoxycarbonyl-4-(4,4,5,5-tetramethyl[1,3,2]dioxaborolan-2-yl)pyrazole, 1-Boc-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole, 1-Boc-4-pyrazoleboronic acid pinacol ester, 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-Boc-pyrazole, 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole-1-carboxylic acid tert-butyl ester, tert-Butyl 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-pyrazolecarboxylate, [1-(tert-Butoxycarbonyl)-1H-pyrazol-4-yl]boronic acid pinacol ester
• Empirical Formula (Hill Notation): C₁₄H₂₃BN₂O₄
• Molecular Weight: 294.15
• MDL number: MFCD05663873
• UNSPSC Code: 12352103
• PubChem Substance ID: 24882509
• NACRES: NA.22

Properties

• Assay: 97%
• form: solid
• mp: 82-86 °C (lit.)
• storage temp.: 2-8°C
• SMILES string: CC(C)(C)OC(=O)n1cc(cn1)B2OC(C)(C)C(C)(C)O2
• InChI: 1S/C14H23BN2O4/c1-12(2,3)19-11(18)17-9-10(8-16-17)15-20-13(4,5)14(6,7)21-15/h8-9H,1-7H3
• InChI key: IPISOFJLWYBCAV-UHFFFAOYSA-N

Description

Application

Reagent used for

• Suzuki Coupling
• Copper-catalyzed azidation

Reagent used in Preparation of

• Selective quinazolinyl-phenol inhibitors of CHK1 as potential antitumors and radioprotectants
• Stereoselective synthesis of selective Cathepsin inhibitors

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves