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283320

Sigma-Aldrich

Butyl lactate

98%

Synonym(s):

α-Hydroxypropionic acid butyl ester, (±)-n-Butyl lactate, 2-Hydroxypropanoic acid butyl ester, Butyl α-hydroxypropionate, Butyl 2-hydroxypropanoate, n-Butyl lactate

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About This Item

Linear Formula:
CH3CH(OH)CO2(CH2)3CH3
CAS Number:
138-22-7
Molecular Weight:
146.18
EC Number:
205-316-4
MDL number:
MFCD00004519
UNSPSC Code:
12352100
PubChem Substance ID:
24857101
NACRES:
NA.22

vapor density

5.04 (vs air)

vapor pressure

0.4 mmHg ( 20 °C)

Assay

98%

form

liquid

refractive index

n20/D 1.421 (lit.)

bp

185-187 °C (lit.)

mp

−28 °C (lit.)

density

0.984 g/mL at 25 °C (lit.)

SMILES string

CCCCOC(=O)C(C)O

InChI

1S/C7H14O3/c1-3-4-5-10-7(9)6(2)8/h6,8H,3-5H2,1-2H3

InChI key

MRABAEUHTLLEML-UHFFFAOYSA-N

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Application

Butyl lactate has been used:
  • in the preparation of solid lipid nanoparticles by a solvent emulsification–diffusion technique
  • in the synthesis of nanoparticles of griseofulvin from water dilutable microemulsions by the solvent diffusion technique
  • as cosurfactant on the preparation of microemulsions with anionic surfactant

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

156.2 °F - closed cup

Flash Point(C)

69 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Michele Trotta et al.
International journal of pharmaceutics, 254(2), 235-242 (2003-03-08)
Nanoparticles of griseofulvin, a model drug with poor solubility and low bioavailability, were prepared from water dilutable microemulsions by the solvent diffusion technique. Solvent-in-water microemulsion formulations containing water, butyl lactate, lecithin, taurodeoxycholate sodium salt (TDC) or dipotassium glycyrrhizinate (KG), 1,2-propanediol
Daniela Chirio et al.
International journal of molecular sciences, 19(12) (2018-12-06)
Chitosan is an excipient which has been studied thoroughly in research works thanks to its positive characteristics such as muco-adhesiveness and ability to open epithelial-tight-junctions. In this article, lipophilic stearoyl chitosan (ST-CS) was synthetized in order to anchor this polymer
Hitomi Ohara et al.
Journal of bioscience and bioengineering, 111(1), 19-21 (2010-09-21)
n-Butyl D- and L-lactates (BuDLa and BuLLa) were incubated with immobilized lipase. (1)H-NMR showed that BuDLa reacted to oligomers, while BuLLa did not react. A mixture containing 90.4% of BuLLa and 9.6% of BuDLa was incubated with the enzyme for
Yunwei Niu et al.
Food research international (Ottawa, Ont.), 131, 108986-108986 (2020-04-06)
Ester aroma compounds in Chinese Moutai Baijiu were extracted by liquid-liquid extraction (LLE) or headspace solid-phase microextraction (HS-SPME) and identified and quantified by gas chromatography-olfactometry (GC-O) and gas chromatography-mass spectrometry (GC-MS), and 13 of them were recognized as the important
Domenico Pirozzi et al.
Biotechnology progress, 22(2), 444-448 (2006-04-08)
The alpha-hydroxy esters are increasingly employed in cosmetic, food, and pharmaceutical formulations as they determine reduced skin-irritant effects in comparison with the respective acids, offering similar hygroscopic, emulsifying, and exfoliating properties. The enzymatic synthesis of lactate esters in nonaqueous systems
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