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234117

Sigma-Aldrich

Oil Red EGN

powder

Synonym(s):

Solvent Red 26

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About This Item

Empirical Formula (Hill Notation):
C25H22N4O
CAS Number:
4477-79-6
Molecular Weight:
394.47
Colour Index Number:
26120
EC Number:
224-757-3
MDL number:
MFCD00009688
UNSPSC Code:
12171500
PubChem Substance ID:
24854021
NACRES:
NA.47

form

powder

composition

Carbon > 64.7%, Nitrogen > 12.1%

mp

130 °C (dec.) (lit.)

λmax

521 nm

ε (extinction coefficient)

≥14000 at 352-360 nm in chloroform at 0.02 g/L
≥25000 at 517-525 nm in chloroform at 0.02 g/L

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

Cc1ccccc1\N=N\c2cc(C)c(cc2C)\N=N\c3c(O)ccc4ccccc34

InChI

1S/C25H22N4O/c1-16-8-4-7-11-21(16)26-27-22-14-18(3)23(15-17(22)2)28-29-25-20-10-6-5-9-19(20)12-13-24(25)30/h4-15,30H,1-3H3/b27-26+,29-28+

InChI key

NRBKWAQSLYBVSG-ZDXBJJIESA-N

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Application

Oil Red EGN has been used to stain lipid droplets accumulated in cell during adipogenesis.

Biochem/physiol Actions

Oil Red EGN is widely used to stain small triglyceride droplets. However, it is not advantageous for staining larger droplets.

Pictograms

Health hazard
GHS08

Signal Word

Warning

Hazard Statements

H351

Precautionary Statements

P201 - P308 + P313

Hazard Classifications

Carc. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Hans Lyon
Theory and Strategy in Histochemistry: A Guide to the Selection and Understanding of Techniques (2012)
An analogue of atrial natriuretic peptide (C-ANP4-23) modulates glucose metabolism in human differentiated adipocytes.
Ruiz-Ojeda FJ
Molecular and Cellular Endocrinology, 431, 101-108 (2016)
Francisco Javier Ruiz-Ojeda et al.
Scientific reports, 9(1), 3979-3979 (2019-03-10)
Tenomodulin (TNMD) is a type II transmembrane glycoprotein that has been recently linked to obesity, and it is highly expressed in obese adipose tissue. Several sex-dependent associations have been observed between single-nucleotide polymorphisms (SNPs) of the TNMD gene, which is
Sivareddy Kotla et al.
Free radical biology & medicine, 76, 147-162 (2014-08-26)
15(S)-Hydroxyeicosatetraenoic acid (15(S)-HETE), the major 15-lipoxygenase 1/2 (15-LO1/2) metabolite of arachidonic acid (AA), induces CD36 expression through xanthine oxidase and NADPH oxidase-dependent ROS production and Syk and Pyk2-dependent STAT1 activation. In line with these observations, 15(S)-HETE also induced foam cell

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