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Merck

Evidence of Aortopathy in Mice with Haploinsufficiency of

Journal of cardiovascular development and disease (2015-04-29)
Sara N Koenig, Kevin M Bosse, Holly A Nadorlik, Brenda Lilly, Vidu Garg
RESUMEN

Thoracic aortic aneurysms (TAA) are a significant cause of morbidity and mortality in humans. While the exact etiology is unknown, genetic factors play an important role. Mutations in