- Chiral separation of thiazide diuretics by HPLC on Chiralcel OD-RH, Chiralcel OJ-R and Chirobiotic-T phases.
Chiral separation of thiazide diuretics by HPLC on Chiralcel OD-RH, Chiralcel OJ-R and Chirobiotic-T phases.
Journal of biochemical and biophysical methods (2002-10-31)
Balázs Visegrády, Tünde Konecsni, Nina Grobuschek, Martin G Schmid, Ferenc Kilár, Hassan Y Aboul-Enein, Gerald Gübitz
PMID12406582
RESUMEN
This contribution deals with comparative studies on the chiral separation of thiazide diuretics using cellulose tris(3,5-dimethylphenylcarbamate) (Chiralcel OD-RH), cellulose tris(4-methylbenzoate) (Chiralcel OJ-R) and teicoplanin (Chirobiotic T) phases. All columns showed good chiral recognition ability for this class of compounds. Out of seven compounds investigated, six were resolved with baseline resolution with at least one of the three columns.
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Columna quiral para HPLC Astec® CHIROBIOTIC® T, 5 μm particle size, L × I.D. 25 cm × 4.6 mm
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Columna quiral para HPLC Astec® CHIROBIOTIC® T, 5 μm particle size, L × I.D. 15 cm × 4.6 mm
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Columna quiral para HPLC Astec® CHIROBIOTIC® T, 5 μm particle size, L × I.D. 15 cm × 2.1 mm
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Columna quiral para HPLC Astec® CHIROBIOTIC® T, 5 μm particle size, L × I.D. 5 cm × 4.6 mm
Supelco
Columna quiral para HPLC Astec® CHIROBIOTIC® T, 5 μm particle size, L × I.D. 10 cm × 2.1 mm
Supelco
Columna quiral para HPLC Astec® CHIROBIOTIC® T, 5 μm particle size, L × I.D. 25 cm × 10 mm
Supelco
Columna quiral para HPLC Astec® CHIROBIOTIC® T, 5 μm particle size, L × I.D. 25 cm × 2.1 mm
Supelco
Columna quiral para HPLC Astec® CHIROBIOTIC® T, 5 μm particle size, L × I.D. 10 cm × 4.6 mm