Saltar al contenido
Merck

New one-pot synthesis of (E)-beta-aryl vinyl halides from styrenes.

Organic letters (2009-07-04)
Piotr Pawluć, Grzegorz Hreczycho, Justyna Szudkowska, Maciej Kubicki, Bogdan Marciniec
RESUMEN

A new, efficient protocol for the highly stereoselective one-pot synthesis of (E)-beta-aryl vinyl iodides and (E)-beta-aryl vinyl bromides from styrenes based on sequential ruthenium-catalyzed silylative coupling-N-halosuccinimide-mediated halodesilylation reactions is reported.

MATERIALES
Referencia del producto
Marca
Descripción del producto

Sigma-Aldrich
Vinyl bromide solution, 1.0 M in THF