- Anti-inflammatory diterpenoids from Croton tonkinensis.
Anti-inflammatory diterpenoids from Croton tonkinensis.
Journal of natural products (2013-01-26)
Ping-Chung Kuo, Mei-Lin Yang, Tsong-Long Hwang, Yuan-Yu Lai, Yue-Chiun Li, Tran Dinh Thang, Tian-Shung Wu
PMID23347584
RESUMEN
Phytochemical investigation of the methanolic extract of Croton tonkinensis afforded two known kauranes (1, 2), eight new ent-kauranes (3-10), and 16 known ent-kaurane-type diterpenoids (12-27). In addition, 30 known compounds were identified by comparison of their physical and spectroscopic data with reported data. Among the isolated compounds, ent-18-acetoxykaur-16-en-15-one (20) displayed the most significant inhibition of superoxide anion generation and elastase release.
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Elastase from porcine pancreas, Type IV, Protein 50-90 %, lyophilized powder, ≥4.0 units/mg protein (biuret)
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Sigma-Aldrich
Elastase from porcine pancreas, Type III, lyophilized powder, Protein 55-85 %, ≥4.0 units/mg protein
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