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Merck
  • Single-step enzymatic synthesis of (R)-2-O-alpha-D-glucopyranosyl glycerate, a compatible solute from micro-organisms that functions as a protein stabiliser.

Single-step enzymatic synthesis of (R)-2-O-alpha-D-glucopyranosyl glycerate, a compatible solute from micro-organisms that functions as a protein stabiliser.

Organic & biomolecular chemistry (2009-10-02)
Thornthan Sawangwan, Christiane Goedl, Bernd Nidetzky
RESUMEN

Regioselective glucosylation of R-glycerate catalysed by sucrose phosphorylase in the presence of sucrose as the donor substrate provided the natural compatible solute (R)-2-O-alpha-D-glucopyranosyl glycerate with complete regioselectivity in an optimised synthetic yield of 90% R-glycerate converted and a concentration of about 270 mM.

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Sigma-Aldrich
Sucrose Phosphorylase, recombinant, expressed in E. coli, lyophilized powder, ≥45 units/mg solid