- A human monoclonal antibody blocking SARS-CoV-2 infection.
A human monoclonal antibody blocking SARS-CoV-2 infection.
Nature communications (2020-05-06)
Chunyan Wang, Wentao Li, Dubravka Drabek, Nisreen M A Okba, Rien van Haperen, Albert D M E Osterhaus, Frank J M van Kuppeveld, Bart L Haagmans, Frank Grosveld, Berend-Jan Bosch
PMID32366817
RESUMEN
The emergence of the novel human coronavirus SARS-CoV-2 in Wuhan, China has caused a worldwide epidemic of respiratory disease (COVID-19). Vaccines and targeted therapeutics for treatment of this disease are currently lacking. Here we report a human monoclonal antibody that neutralizes SARS-CoV-2 (and SARS-CoV) in cell culture. This cross-neutralizing antibody targets a communal epitope on these viruses and may offer potential for prevention and treatment of COVID-19.
MATERIALES
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Descripción del producto
Sigma-Aldrich
Cell Dissociation Solution Non-enzymatic 1x, Prepared in phosphate buffered saline without calcium and magnesium, sterile-filtered, BioReagent, suitable for cell culture
Millipore
Proteína G-agarosa, flujo rápido, Protein G Agarose, Fast Flow suitable for medium and low pressure chromatography of IgG from mouse, sheep, and rabbit, and for immunoprecipitations.