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Merck

S7896

Sigma-Aldrich

Syringaldazine

indicator for laccase and peroxidase activity, ≥98% (TLC), powder or crystals

Sinónimos:

4-Hydroxy-3,5-dimethoxybenzaldehyde azine

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About This Item

Fórmula lineal:
[HOC6H2(OCH3)2CH=N-]2
Número de CAS:
Peso molecular:
360.36
EC Number:
MDL number:
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.83

product name

Syringaldazine, indicator for laccase and peroxidase activity

assay

≥98% (TLC)

form

powder or crystals

mp

209-210 °C (lit.)

solubility

DMF: soluble, slightly hazy

storage temp.

2-8°C

SMILES string

COc1cc(\C=N\N=C\c2cc(OC)c(O)c(OC)c2)cc(OC)c1O

InChI

1S/C18H20N2O6/c1-23-13-5-11(6-14(24-2)17(13)21)9-19-20-10-12-7-15(25-3)18(22)16(8-12)26-4/h5-10,21-22H,1-4H3/b19-9+,20-10+

InChI key

YARKTHNUMGKMGS-LQGKIZFRSA-N

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Application

Syringaldazine has been used as a substrate to determine the enzymatic activity of the cuticular laccase.

Biochem/physiol Actions

Syringaldazine is a dimer of two molecules of 2,6-dimethoxyphenol linked by an azide bridge. It is a phenolic non-autooxidizable laccase-specific compound, that facilitates the detection of fungal laccase in some varieties of fungi. In addition, it also acts as an indicator for peroxidase activity in fungi.

pictograms

Flame

signalword

Warning

hcodes

pcodes

Hazard Classifications

Flam. Sol. 2

Storage Class

4.1B - Flammable solid hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


Certificados de análisis (COA)

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Quantitative estimation of laccase forms in some white-rot fungi using syringaldazine as a substrate
Leonowicz A and Grzywnowicz K
Enzyme and Microbial Technology, 3(1), 55-58 (1981)
Use of syringaldazine for detection of laccase in sporophores of wood rotting fungi
Harkin JM, et al.
Mycologia, 66(3), 469-476 (1974)
Aptitude of Oxidative Enzymes for Treatment of Wastewater Pollutants: A Laccase Perspective
Unuofin JO, et al.
Molecules (Basel), 24(11), 2064-2064 (2019)
Characterization of endogenous and recombinant forms of laccase-2, a multicopper oxidase from the tobacco hornworm, Manduca sexta
Dittmer NT, et al.
Insect Biochemistry and Molecular Biology, 39(9), 596-606 (2009)
Syringaldazine, an effective reagent for detecting laccase and peroxidase in fungi
Harkin JM and Obst JR
Experientia, 29(4), 381-387 (1973)

Protocolos

Laccase, a biocatalyst, oxidizes aromatic compounds with molecular oxygen reduction, making it useful in various applications.

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