247588

Salicylic acid

ACS reagent, ≥99.0%

• Sinónimos: 2-Hydroxybenzoic acid
• Fórmula lineal: 2^-(HO)C₆H₄CO₂H
• Número de CAS: 69-72-7
• Peso molecular: 138.12
• Beilstein/REAXYS Number: 774890
• EC Number: 200-712-3
• MDL number: MFCD00002439
• UNSPSC Code: 12352100
• PubChem Substance ID: 24854876
• NACRES: NA.21

Propiedades

• grade: ACS reagent
• Quality Level: 200
• vapor density: 4.8 (vs air)
• vapor pressure: 1 mmHg ( 114 °C)
• assay: ≥99.0%
• impurities: H₂SO₄, passes test (darkened)
• ign. residue: ≤0.01%
• bp: 211 °C (lit.)
• mp: 158-161 °C (lit.)
• anion traces: chloride (Cl^-): ≤0.001%; sulfate (SO₄^2-): ≤0.003%
• cation traces: Fe: ≤2 ppm; heavy metals (as Pb): ≤5 ppm
• SMILES string: OC(=O)c1ccccc1O
• InChI: 1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)
• InChI key: YGSDEFSMJLZEOE-UHFFFAOYSA-N
• Gene Information: human ... ALB(213) , PTPN1(5770)

Descripción

General description

Salicylic acid is mainly used as the precursor to synthesize aspirin, a commonly used analgesic and antipyretic. Due to its keratolytic action, it is also used in topical ointments.

application

Salicylic acid has been used:

• as one of the chemical compound in exposure-based validation of in vitro gastrulation model employed in developmental toxicity screening assays
• as a reference standard in salicylate quantification by reverse-phase high-performance liquid chromatography (RP-HPLC)

Biochem/physiol Actions

Salicylic acid (SA) delivers local and systemic acquired resistance (LAR and SAR) against various diseases in plants. It acts as a secondary metabolite and regulate various physiological processes such as respiration, stomatal closure and senescence-associated gene expression. In addition, SA also controls abiotic stress, basal thermotolerance, nodulation in legumes and fruit yield. It plays a vital role in modulation of flowering and thermogenesis (heat production) in plants. SA together with reactive oxygen species (ROS) and nitric oxide (NO) triggers cell death in plants.

Información de seguridad

• pictograms: GHS08,GHS05,GHS07
• signalword: Danger
• hcodes: H302,H318,H361d
• pcodes: P202 - P264 - P280 - P301 + P312 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 2
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: 314.6 °F - closed cup
• flash_point_c: 157 °C - closed cup
• ppe: dust mask type N95 (US), Eyeshields, Gloves