415758

5′-Chloro-2′-hydroxy-4′-methylacetophenone

98%

• Fórmula lineal: ClC₆H₂(OH)(CH₃)COCH₃
• Número de CAS: 28480-70-8
• Peso molecular: 184.62
• MDL number: MFCD00191920
• UNSPSC Code: 12352100
• PubChem Substance ID: 24866031
• NACRES: NA.22

Propiedades

• assay: 98%
• mp: 70-73 °C (lit.)
• SMILES string: CC(=O)c1cc(Cl)c(C)cc1O
• InChI: 1S/C9H9ClO2/c1-5-3-9(12)7(6(2)11)4-8(5)10/h3-4,12H,1-2H3
• InChI key: HDUSGGZSLVCDKY-UHFFFAOYSA-N

Descripción

General description

5′-chloro-2′-hydroxy-4′-methylacetophenone (5-Chloro-2-hydroxy-4-methylacetophenone) is a hydroxylated aromatic acetophenone. Its iodination by pyridinium iodochloride has been reported to afford 5-chloro-2-hydroxy-3-iodo-4-methylacetophenone.

Application

5′-Chloro-2′-hydroxy-4′-methylacetophenone (5-chloro-2-hydroxy-4-methylacetophenone) may be used in the preparation of the following:

• chalcones, required for the synthesis of novel pyrazoline derivatives
• 5′-chloro-2′-hydroxy-4′-methyl-3-(2´´-thienyl)acrylophenone
• 6-chloro-3-hydroxy-7-methyl-2-(2-thienyl)-4H-chromen-4-one, a complexing agent used for the spectrophotometric determination of vanadium(V)

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves