381551

7-Isopropoxy-3-phenyl-4H-1-benzopyran-4-one

97%

• Sinónimos: Ipriflavone
• Fórmula empírica (notación de Hill): C₁₈H₁₆O₃
• Número de CAS: 35212-22-7
• Peso molecular: 280.32
• MDL number: MFCD00221719
• UNSPSC Code: 12352100
• PubChem Substance ID: 24863826
• NACRES: NA.22

Propiedades

• assay: 97%
• mp: 116-120 °C (lit.)
• SMILES string: CC(C)Oc1ccc2c(OC=C(C2=O)c3ccccc3)c1
• InChI: 1S/C18H16O3/c1-12(2)21-14-8-9-15-17(10-14)20-11-16(18(15)19)13-6-4-3-5-7-13/h3-12H,1-2H3
• InChI key: SFBODOKJTYAUCM-UHFFFAOYSA-N
• Gene Information: rat ... Alpl(25586)

Descripción

General description

7-Isopropoxy-3-phenyl-4H-1-benzopyran-4-one (Ipriflavone), a synthetic flavonoid, is reported to stimulate the activity of osteoblasts. It is reported to promote the deposition of calcium and the formation of mineralized nodules by newborn rat calvarial osteoblast-like (ROB) cells as well as the activity of alkaline phosphatase. Ipriflavone, an isoflavone derivative, is a new drug used to decrease bone loss in osteoporosis.

Application

7-Isopropoxy-3-phenyl-4H-1-benzopyran-4-one (Ipriflavone) has been used as a model drug in a study to functionalize the mesoporous bioactive glasses (MBG). Study suggested that since ipriflavone is a hydrophobic anti-osteoporotic drug, it easily attaches to the surface of MBG and results in long-term drug delivery.

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)