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144630

Sigma-Aldrich

α-Cyano-3-hydroxycinnamic acid

98%

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About This Item

Fórmula lineal:
HOC6H4CH=C(CN)CO2H
Número de CAS:
54673-07-3
Peso molecular:
189.17
EC Number:
259-289-9
MDL number:
MFCD00004203
UNSPSC Code:
12352100
PubChem Substance ID:
24848676

assay

98%

mp

232 °C (dec.) (lit.)

SMILES string

OC(=O)\C(=C\c1cccc(O)c1)C#N

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificados de análisis (COA)

Lot/Batch Number
08629MH
08720MN
07816ML

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H K Metcalfe et al.
Clinical science (London, England : 1979), 71(6), 755-761 (1986-12-01)
The rate of efflux of ketone bodies has been studied in isolated hepatocytes prepared from starved rats and preloaded with D-3-[14C]hydroxybutyrate. Efflux of ketone bodies was temperature-dependent, saturable and inhibited by alpha-cyano-3-hydroxycinnamate and phloretin. The rate of efflux was also
S M Hutson et al.
The Journal of biological chemistry, 260(26), 14189-14193 (1985-11-15)
Efflux of branched chain alpha-keto acids from preloaded rat heart mitochondria was slow at low external pH. Efflux was first order, and measured rate constants, kappa efflux, were 0.104 +/- 0.005 and 0.115 +/- 0.006 min-1 for alpha-ketoisovalerate and alpha-ketoisocaproate
Rie Hosoi et al.
Brain research, 1253, 69-73 (2008-12-17)
To investigate the regulation mechanism of (14)C-acetate uptake in astrocytes, uptake experiments with cultured rat astrocytes were performed. In this study, we used a relatively low concentration (0.0185 mM) of (14)C-acetate. The uptake was dependent on pH and acetate concentration
J P Monson et al.
Clinical science (London, England : 1979), 62(4), 411-420 (1982-04-01)
1. The rate of uptake in 15 s of L- and D-lactate was studied in isolated hepatocyte preparations from starved rats. 2. Observations were also made of the effect of different concentrations of unlabelled L- and D-lactate on L-[14C]- and
I E O'Neill et al.
Comparative biochemistry and physiology. B, Comparative biochemistry, 83(3), 595-598 (1986-01-01)
Isolated kidney tubules synthesize glucose actively from fructose, lactate, glycerol and pyruvate and, to a lesser extent, from a variety of amino acids. Ethanol stimulated gluconeogenesis from pyruvate and inhibited it from lactate. The aminotransferase inhibitor, aminooxyacetate, greatly reduced synthesis
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