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100870

Sigma-Aldrich

Bis(4-chlorophenyl)acetic acid

98%

Sinónimos:

4,4′-DDA

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About This Item

Fórmula lineal:
(ClC6H4)2CHCO2H
Número de CAS:
83-05-6
Peso molecular:
281.13
EC Number:
201-451-8
MDL number:
MFCD00004248
UNSPSC Code:
12352100
PubChem Substance ID:
24846425

assay

98%

mp

167-169 °C (lit.)

SMILES string

OC(=O)C(c1ccc(Cl)cc1)c2ccc(Cl)cc2

InChI

1S/C14H10Cl2O2/c15-11-5-1-9(2-6-11)13(14(17)18)10-3-7-12(16)8-4-10/h1-8,13H,(H,17,18)

InChI key

YIOCIFXUGBYCJR-UHFFFAOYSA-N

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Karsten Hemmrich et al.
Cytotherapy, 12(4), 547-553 (2010-04-08)
Obesity is correlated with chronic low-grade inflammation. Thus the induction of inflammation could be used to stimulate adipose tissue formation in tissue-engineering approaches. As nitric oxide (NO) is a key regulator of inflammation, we investigated the effect of NO and
J Guilford et al.
Drug and chemical toxicology, 9(3-4), 239-252 (1986-01-01)
The possibility that lead could affect the metabolism of the insecticide 1,1-dichloro-2, 2-bis(p-chlorophenyl)ethane, DDD, was examined by studies of the effects of chronic oral Pb treatment on DDD conversion to 2,2-bis(p-chlorophenyl)acetic acid, DDA. Rats were given either distilled deionized water
W K Nichols et al.
Drug metabolism and disposition: the biological fate of chemicals, 23(5), 595-599 (1995-05-01)
Isolated rabbit Clara cells and a transformed human bronchial epithelial cell line, BEAS-2B, were used to investigate the mechanism of cytotoxicity of 1,1-dichloro-2,2-bis(p-chlorophenyl)ethane (DDD), a persistent insecticide and stable metabolite of 1,1,1-trichloro-2,2- bis(p-chlorophenyl)ethane. Both BEAS-2B cells and rabbit Clara cells
Mitotane (1-(o-chlorophenyl)-1-(p-chlorophenyl)-2,2-dichloroethane) metabolism in perfusion studies with dog adrenal glands.
J E Sinsheimer et al.
Drug metabolism and disposition: the biological fate of chemicals, 15(2), 267-269 (1987-03-01)
H van Dijk et al.
Methods and findings in experimental and clinical pharmacology, 8(3), 189-193 (1986-03-01)
A novel, sensitive system to determine immunological adjuvant activity is presented. It is based on the direct haemagglutinin response of mice to neuraminidase-treated sheep red blood cells (asialo-SRBC) seven days after i.p. immunization. For two model adjuvants it is shown
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