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Merck

ZNF384

zinc finger protein 384

Sinónimos:
CAGH1, CAGH1A, CIZ, ERDA2, NMP4, NP, TNRC1
Especie:
ID UniProtKB:
ID del gen:
  • Human(171017) Summary: This gene encodes a C2H2-type zinc finger protein, which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewing's sarcoma gene, EWSR1 on chromosome 22, or with the TAF15 gene on chromosome 17, or with the TCF3 (E2A) gene on chromosome 19, have been observed in acute leukemia. A related pseudogene has been identified on chromosome 7. [provided by RefSeq, Apr 2011]
  • sheep(101111704) zinc finger protein 384
  • domestic guinea pig(100726713) zinc finger protein 384
  • naked mole-rat(101711787) zinc finger protein 384
  • domestic cat(101083184) zinc finger protein 384
  • dog(486723) zinc finger protein 384
  • chicken(770350) zinc finger protein 384
  • cow(515007) zinc finger protein 384
  • Horse(100059879) zinc finger protein 384

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esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human ZNF384, RP4-761J14.8,
Especie
human