UHRF1
ubiquitin-like with PHD and ring finger domains 1
Sinónimos:
ICBP90, Np95, RNF106, hNP95, hUHRF1
Especie:
Human UHRF1 (29128), Mouse Uhrf1 (18140), Rat Uhrf1 (316129), chicken UHRF1 (420154), Zebrafish uhrf1 (406350), Zebrafish uhrf1 (100538017), naked mole-rat Uhrf1 (101719703), domestic guinea pig Uhrf1 (100719542), sheep UHRF1 (101113067), cow UHRF1 (530411) ...Más
ID UniProtKB:
ID del gen:
- Human(29128) Summary: This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(18140) ubiquitin-like, containing PHD and RING finger domains, 1
- Rat(316129) ubiquitin-like with PHD and ring finger domains 1
- chicken(420154) ubiquitin-like with PHD and ring finger domains 1
- Zebrafish(406350) ubiquitin-like, containing PHD and RING finger domains, 1
- Zebrafish(100538017) ubiquitin-like with PHD and ring finger domains 1
- naked mole-rat(101719703) ubiquitin-like with PHD and ring finger domains 1
- domestic guinea pig(100719542) ubiquitin-like with PHD and ring finger domains 1
- sheep(101113067) ubiquitin-like with PHD and ring finger domains 1
- cow(530411) ubiquitin-like with PHD and ring finger domains 1
- Horse(100062347) ubiquitin-like with PHD and ring finger domains 1
- domestic cat(101083658) ubiquitin-like with PHD and ring finger domains 1
- dog(611463) ubiquitin-like with PHD and ring finger domains 1
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-ICBP90/UHRF1 Antibody, clone 1RC1C-10, ascites fluid, clone 1RC-1C10, from mouse,
Reactividad de especies
human
Aplicación
ChIP
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-E3 ubiquitin-protein ligase UHRF1, clone BF18.11 Antibody, clone BF18.11, from mouse,
Reactividad de especies
mouse
Aplicación
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-UHRF1 Mouse mAb (3A11), liquid, clone 3A11, Calbiochem®,
Reactividad de especies
human
Aplicación
Anti-E3 ubiquitin-protein ligase UHRF1 Antibody, clone 7C8, clone 7C8, 1 mg/mL, from mouse,
Reactividad de especies
human
Aplicación
ChIP
immunocytochemistry
western blot
immunocytochemistry
western blot
Anti-E3 ubiquitin-protein ligase UHRF1 Antibody, from rabbit, purified by affinity chromatography,
Reactividad de especies
bovine, canine, feline, horse, human, porcine, primate
Aplicación
immunohistochemistry
western blot
western blot