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Merck

TSG101

tumor susceptibility 101

Sinónimos:
TSG10, VPS23
Especie:
ID UniProtKB:
ID del gen:
  • Human(7251) Summary: The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression. [provided by RefSeq, Jul 2008]
  • Mouse(22088) tumor susceptibility gene 101
  • Rat(292925) tumor susceptibility gene 101
  • Zebrafish(415179) tumor susceptibility gene 101
  • sheep(101118061) tumor susceptibility gene 101
  • Domestic Rabbit(100343429) tumor susceptibility gene 101
  • Goat(100861362) tumor susceptibility gene 101
  • domestic guinea pig(100713139) tumor susceptibility gene 101
  • Horse(100057099) tumor susceptibility gene 101
  • fruit fly(39881) tumor suppressor protein 101
  • cow(507659) tumor susceptibility gene 101
  • naked mole-rat(101716856) tumor susceptibility gene 101
  • domestic cat(101100915) tumor susceptibility gene 101
  • dog(485406) tumor susceptibility gene 101
  • chicken(423082) tumor susceptibility gene 101

Custom & Knockdown Gene Products

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-TSG101/VPS23 Antibody, clone 4T4W6, Rabbit Monoclonal, ,
Reactividad de especies
human, rat
Aplicación
western blot
Anti-TSG101 (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
bovine, canine, goat, guinea pig, horse, human, mouse, rabbit, zebrafish
Aplicación
immunohistochemistry
western blot
Anti-TSG101 (C-terminal) antibody produced in rabbit, ~1.5 mg/mL, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
human, mouse, rat
Aplicación
western blot

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting human TSG101,
Especie
human
MISSION® esiRNA, targeting mouse Tsg101,
Especie
mouse