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Merck

TREM2

triggering receptor expressed on myeloid cells 2

Sinónimos:
TREM-2, Trem2a, Trem2b, Trem2c
Especie:
ID UniProtKB:
ID del gen:
  • Human(54209) Summary: This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012]
  • Mouse(83433) triggering receptor expressed on myeloid cells 2
  • Rat(301227) triggering receptor expressed on myeloid cells 2
  • sheep(101105447) triggering receptor expressed on myeloid cells 2
  • cow(506467) triggering receptor expressed on myeloid cells 2
  • domestic cat(101099297) triggering receptor expressed on myeloid cells 2
  • dog(608965) triggering receptor expressed on myeloid cells 2
  • chicken(419920) triggering receptor expressed on myeloid cells 2
  • naked mole-rat(101717064) triggering receptor expressed on myeloid cells 2
  • domestic guinea pig(100720722) triggering receptor expressed on myeloid cells 2

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-TREM-2 Antibody, clone 78, clone 78, from rat,
Reactividad de especies
human, mouse, rat
Aplicación
flow cytometry
immunocytochemistry

immunoprecipitation (IP)

inhibition assay

western blot
Anti-TREM-2, from rabbit, purified by affinity chromatography,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
Anti-TREM-2 Antibody, clone 10H4.2, clone 10H4.2, from mouse,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
Anti-TREM-2 Antibody, clone 1I11 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, mouse
Aplicación
affinity binding assay
flow cytometry

immunocytochemistry

western blot

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human TREM2,
Especie
human
MISSION® esiRNA, targeting mouse Trem2,
Especie
mouse