TNFSF15
tumor necrosis factor (ligand) superfamily, member 15
Sinónimos:
TL1, TL1A, VEGI, VEGI192A
Especie:
Human TNFSF15 (9966), Mouse Tnfsf15 (326623), Rat Tnfsf15 (252878), domestic cat TNFSF15 (101099505), chicken TNFSF15 (417247), naked mole-rat Tnfsf15 (101720658), domestic guinea pig Tnfsf15 (100725797), sheep TNFSF15 (101102957), dog TNFSF15 (481688), cow TNFSF15 (514239)
ID UniProtKB:
ID del gen:
- Human(9966) Summary: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]
- Mouse(326623) tumor necrosis factor (ligand) superfamily, member 15
- Rat(252878) tumor necrosis factor (ligand) superfamily, member 15
- domestic cat(101099505) tumor necrosis factor (ligand) superfamily, member 15
- chicken(417247) tumor necrosis factor (ligand) superfamily, member 15
- naked mole-rat(101720658) tumor necrosis factor (ligand) superfamily, member 15
- domestic guinea pig(100725797) tumor necrosis factor (ligand) superfamily, member 15
- sheep(101102957) tumor necrosis factor (ligand) superfamily, member 15
- dog(481688) tumor necrosis factor (ligand) superfamily, member 15
- cow(514239) tumor necrosis factor (ligand) superfamily, member 15
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