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Merck

TNFRSF4

tumor necrosis factor receptor superfamily, member 4

Sinónimos:
ACT35, CD134, OX40, TXGP1L
Especie:
ID UniProtKB:
ID del gen:
  • Human(7293) Summary: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq, Jul 2008]
  • Mouse(22163) tumor necrosis factor receptor superfamily, member 4
  • Rat(25572) tumor necrosis factor receptor superfamily, member 4
  • domestic guinea pig(100715179) tumor necrosis factor receptor superfamily, member 4
  • cow(528782) tumor necrosis factor receptor superfamily, member 4
  • Domestic Rabbit(100009449) tumor necrosis factor receptor superfamily, member 4
  • chicken(101751037) tumor necrosis factor receptor superfamily, member 4
  • sheep(101108407) tumor necrosis factor receptor superfamily, member 4
  • naked mole-rat(101714706) tumor necrosis factor receptor superfamily, member 4
  • domestic cat(493665) tumor necrosis factor receptor superfamily, member 4
  • chicken(101665445) tumor necrosis factor receptor superfamily, member 4
  • dog(489600) tumor necrosis factor receptor superfamily, member 4

Custom & Knockdown Gene Products

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-TNFRSF4 Antibody, clone 3N2 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human
Aplicación
ELISA
affinity binding assay

immunocytochemistry

western blot